2024
A Comprehensive, Artificial Intelligence, Digital Twin Platform Based on Multimodal Real-World Data Integration for Personalized Medicine in Hematology
D'Amico S, Sauta E, Asti G, Delleani M, Zazzetti E, Campagna A, Lanino L, Maggioni G, Ubezio M, Todisco G, Russo A, Tentori C, Buizza A, Franchi M, Dall'Olio L, Bicchieri M, Zampini M, Brindisi M, Ficara F, Riva E, Ventura D, Crisafulli L, Pinocchio N, Della Porta A, Jacobs F, Zambelli A, Savevski V, Santoro A, Sole F, Platzbecker U, Fenaux P, Diez-Campelo M, Garcia-Manero G, Haferlach T, Kordasti S, Castellani G, Efficace F, Santini V, Zeidan A, Komrokji R, Della Porta M. A Comprehensive, Artificial Intelligence, Digital Twin Platform Based on Multimodal Real-World Data Integration for Personalized Medicine in Hematology. Blood 2024, 144: 2221-2221. DOI: 10.1182/blood-2024-209634.Peer-Reviewed Original ResearchArtificial intelligenceData sharingDigital twinFederated learning platformSynthetic data generatorSHapley Additive exPlanationsImage dataDT platformDecision support systemMultimodal longitudinal dataAI-based toolsUnstructured informationAI frameworkData model formatElectronic health recordsMultimodal dataMultimodal informationPatient informationData integrationAI modelsData generationCentral repositoryTechnology implementation methodMultiple sources of informationReal world
2023
Synthetic Histopathological Images Generation with Artificial Intelligence to Accelerate Research and Improve Clinical Outcomes in Hematology
Asti G, D'Amico S, Curti N, Carlini G, Sauta E, Derus N, Dall'Olio D, Sala C, Dall'Olio L, Lanino L, Maggioni G, Campagna A, Ubezio M, Russo A, Todisco G, Tentori C, Morandini P, Bicchieri M, Grondelli M, Zampini M, Savevski V, Santoro A, Kordasti S, Santini V, Kubasch A, Platzbecker U, Diez-Campelo M, Fenaux P, Zhao L, Zeidan A, Haferlach T, Castellani G, Della Porta M. Synthetic Histopathological Images Generation with Artificial Intelligence to Accelerate Research and Improve Clinical Outcomes in Hematology. Blood 2023, 142: 902. DOI: 10.1182/blood-2023-187521.Peer-Reviewed Original ResearchData augmentationArtificial intelligenceSynthetic imagesTextual inputGenerative modelDomain-specific language modelsAvailable textual dataSynthetic data augmentationEffective data augmentationFeatures of imagesReal-world datasetsSynthetic data generationReal-world imagesSpecific language modelHistological imagesUse casesImage featuresData sharingMultimodal dataImage generationTextual dataLayers of informationLanguage modelMultimodal informationClassification performance