Generation of Multimodal Longitudinal Synthetic Data By Artificial Intelligence to Improve Personalized Medicine in Hematology
D'Amico S, Delleani M, Sauta E, Asti G, Zazzetti E, Campagna A, Lanino L, Maggioni G, Ubezio M, Todisco G, Russo A, Tentori C, Buizza A, Bicchieri M, Zampini M, Brindisi M, Ficara F, Riva E, Ventura D, Crisafulli L, Pinocchio N, Jacobs F, Zambelli A, Savevski V, Santoro A, Sanavia T, Rollo C, Sartori F, Fariselli P, Sanz G, Santini V, Sole F, Platzbecker U, Fenaux P, Diez-Campelo M, Kordasti S, Komrokji R, Garcia-Manero G, Haferlach T, Zeidan A, Castellani G, Della Porta M. Generation of Multimodal Longitudinal Synthetic Data By Artificial Intelligence to Improve Personalized Medicine in Hematology. Blood 2024, 144: 4981-4981. DOI: 10.1182/blood-2024-209541.Peer-Reviewed Original ResearchDeep learning-based frameworkLearning-based frameworkPrivacy preservationSynthetic dataSynthetic patientsPerformance of classificationXGBoost classification modelDisease classificationPrivacy-compliantConditional GANPrivacy protectionPrivacy risksLanguage modelGeneration pipelineMultimodal featuresFeature distributionGenerative AIMultimodal dataModel trainingMosaic frameworkClassification modelData integrationArtificial intelligencePrivacyClipping moduleA Comprehensive, Artificial Intelligence, Digital Twin Platform Based on Multimodal Real-World Data Integration for Personalized Medicine in Hematology
D'Amico S, Sauta E, Asti G, Delleani M, Zazzetti E, Campagna A, Lanino L, Maggioni G, Ubezio M, Todisco G, Russo A, Tentori C, Buizza A, Franchi M, Dall'Olio L, Bicchieri M, Zampini M, Brindisi M, Ficara F, Riva E, Ventura D, Crisafulli L, Pinocchio N, Della Porta A, Jacobs F, Zambelli A, Savevski V, Santoro A, Sole F, Platzbecker U, Fenaux P, Diez-Campelo M, Garcia-Manero G, Haferlach T, Kordasti S, Castellani G, Efficace F, Santini V, Zeidan A, Komrokji R, Della Porta M. A Comprehensive, Artificial Intelligence, Digital Twin Platform Based on Multimodal Real-World Data Integration for Personalized Medicine in Hematology. Blood 2024, 144: 2221-2221. DOI: 10.1182/blood-2024-209634.Peer-Reviewed Original ResearchArtificial intelligenceData sharingDigital twinFederated learning platformSynthetic data generatorSHapley Additive exPlanationsImage dataDT platformDecision support systemMultimodal longitudinal dataAI-based toolsUnstructured informationAI frameworkData model formatElectronic health recordsMultimodal dataMultimodal informationPatient informationData integrationAI modelsData generationCentral repositoryTechnology implementation methodMultiple sources of informationReal world