2023
13. Assessing Clinical Care Experiences of Patients with Congenital Uterine Anomalies: a Pilot Study
Saleh F, Vash-Margita A, Margetts M, Pelosi E. 13. Assessing Clinical Care Experiences of Patients with Congenital Uterine Anomalies: a Pilot Study. Journal Of Pediatric And Adolescent Gynecology 2023, 36: 179. DOI: 10.1016/j.jpag.2023.01.101.Peer-Reviewed Original ResearchCongenital uterine anomaliesTertiary healthcare systemUterine anomaliesPatient experienceAdverse pregnancy outcomesInitial presenting symptomMajority of patientsTertiary care settingClinical care experiencesHealthcare systemKuster-Hauser syndromePatient-centered outcomes researchAge 13 yearsDidelphys uterusGynecologic outcomesPoor obstetricPresenting symptomPregnancy outcomesMayer-RokitanskyPregnancy lossCongenital anomaliesHigh prevalenceCare settingsClinical careAverage age
2021
The Embryological Landscape of Mayer-Rokitansky-Kuster-Hauser Syndrome: Genetics and Environmental Factors.
Kyei-Barffour I, Margetts M, Vash-Margita A, Pelosi E. The Embryological Landscape of Mayer-Rokitansky-Kuster-Hauser Syndrome: Genetics and Environmental Factors. The Yale Journal Of Biology And Medicine 2021, 94: 657-672. PMID: 34970104, PMCID: PMC8686787.Peer-Reviewed Original ResearchConceptsMRKH syndromeClinical presentationMayer-RokitanskyEmbryonic developmentEnvironmental factorsEpigenetic changesFunctional validationCandidate genesGenetic analysisMolecular mechanismsDevelopmental pathwaysKüster-Hauser syndromeEarly organogenesisKuster-Hauser syndromeKey pathwaysGenetic componentInheritance patternEnvironmental compoundsIncomplete penetranceClinical managementDiscordant phenotypesEarly diagnosisAnimal modelsGeneticsTranslational studies