Nasal Swabs Could Help Identify Emerging Viruses, Yale Researchers Say
The researchers are looking for little known viruses in certain samples to try to identify new diseases before they become a threat. “COVID came as a surprise. All of the sudden, there was an outbreak, and people discovered that there was a new virus that could cause an illness,” Dr. Ellen Foxman, Yale School of Medicine immunologist, said. “What we want to do going forward is be able to get ahead of that.”Source: NBC News CT
Postdoctoral positions available in the Liu lab, Microbial Sciences Institute at Yale University
Postdoctoral positions are available in the Liu lab in the Microbial Sciences Institute at Yale University to participate in cutting-edge research using high-throughput cryo-ET technology to determine the structural mechanisms of molecular machines essential for bacterial pathogenesis and viral infection.
Rigor in Experimental design and Analysis of Data (READ)
We talk a lot about the role that physician-scientists play as “interpreters” and “translators” between the worlds of medicine and research. But that often means stepping outside of one’s narrow area of scientific expertise to help colleagues and trainees understand clinically relevant data that informs patient care, even if it’s far from what you look at in your own research.
CT COVID hospitalizations are up nearly 60% from a month ago
Connecticut’s COVID hospitalizations have risen by 58% over the last four weeks, and with families and colleagues preparing to gather for the holidays, health officials are urging people to don masks indoors and consider the well-being of others as they go about the seasonal bustle.Source: CT Mirror
Long COVID: Skeptics Are Wrong, Researchers Say
WHRY collaborator Akiko Iwasaki, PhD, joins Fiona Lowenstein, editor of “The Long COVID Survival Guide,” to discuss patients who say they’re suffering from Long COVID for as much as two years after their acute phase of the disease. Listen to their discussion as part of "Conversations on Health Care."Source: Community Health Center
Yale Department of Internal Medicine Celebrates Top Female Scientists
Last month, Research.com published the Best Female Scientists in 2022. The results were based on a ranking system which measures the impact of a researcher’s publications by combining the number of papers they have published and how often they are cited by other papers. 623 U.S.-based researchers appeared in list with three women representing the Yale Department of Internal Medicine.
What is it Like to Live with Brain Fog?
Akiko Iwasaki, Yale professor of immunobiology and WHRY collaborator, is the co-author of a review article on Covid-19 related cognitive impairment. The condition has affected people with cancer and other chronic conditions for years, but long Covid is just beginning to push it into the spotlight.Source: Washington Post
Competition between respiratory viruses may hold off a ‘tripledemic’ this winter
A growing body of evidence suggests that SARS-CoV-2 and other respiratory viruses often “interfere” with each other. Although waves of each virus may stress emergency rooms and intensive care units, the small clique of researchers who study these viral collisions say there is little chance the trio will peak together and collectively crash hospital systems the way COVID-19 did at the pandemic’s start.Source: Science
Mismatch Repair Genes May Be Key to Immunotherapy Response
A new study by Yale School of Medicine researchers has identified a possible explanation for why some cancers don’t respond to immunotherapy. In an analysis of a Phase II trial investigating the immunotherapy drug pembrolizumab in 24 patients with endometrial cancer, the team found faulty DNA repair in tumors was a key factor in determining patient outcomes. The study was published in Cancer Discovery.Source: Inside Precision Medicine
Will Long COVID Research Provide Answers for Poorly Understood Diseases Like ME/CFS?
ME/CFS (myalgic encephalomyelitis/chronic fatigue syndrome) is a highly disabling, severe condition that has been largely overlooked and even questioned as an illness by physicians and biomedical researchers for decades. But now, scientists including Yale's Akiko Iwasaki and Harlan Krumholz are finding parallels between post-infection long COVID and ME/CFS.
COVID-19 Virus Increases Risk for Other Infections by Disrupting Normal Mix of Gut Bacteria
Infection with the pandemic virus, SARS-CoV-2, can reduce the number of bacterial species in a patient’s gut, with the lesser diversity creating space for dangerous microbes to thrive, a new study finds.Source: NYU Langone Health