2017
Acting on identity: Myoblast fusion and the formation of the syncytial muscle fiber
Deng S, Azevedo M, Baylies M. Acting on identity: Myoblast fusion and the formation of the syncytial muscle fiber. Seminars In Cell And Developmental Biology 2017, 72: 45-55. PMID: 29101004, PMCID: PMC5910025, DOI: 10.1016/j.semcdb.2017.10.033.Peer-Reviewed Original Research
2016
Diaphanous regulates SCAR complex localization during Drosophila myoblast fusion
Deng S, Bothe I, Baylies M. Diaphanous regulates SCAR complex localization during Drosophila myoblast fusion. Fly 2016, 10: 178-186. PMID: 27314572, PMCID: PMC5036928, DOI: 10.1080/19336934.2016.1195938.Peer-Reviewed Original ResearchConceptsArp2/3 activationMyoblast fusionFusion siteSCAR activityDrosophila myoblast fusionBranched actin networksRegulate actin dynamicsActin cytoskeletal rearrangementDrosophila to manExtra View articleLoss of SCARCell-cell fusionOrganizing actinActin dynamicsActin rearrangementActin networkCytoskeletal rearrangementsSite of fusionMultinucleated muscle cellsActinComplex localizationDrosophilaWaspsView articleModel system
2015
The Formin Diaphanous Regulates Myoblast Fusion through Actin Polymerization and Arp2/3 Regulation
Deng S, Bothe I, Baylies M. The Formin Diaphanous Regulates Myoblast Fusion through Actin Polymerization and Arp2/3 Regulation. PLOS Genetics 2015, 11: e1005381. PMID: 26295716, PMCID: PMC4546610, DOI: 10.1371/journal.pgen.1005381.Peer-Reviewed Original ResearchConceptsF-actin fociF-actinActin polymerizationCell-cell fusionPodosome formationMyoblast fusionFusion siteElongation of actin filamentsRegulation of actin polymerizationLoss-of-function conditionsActin turnover rateBranched actin regulatorsDrosophila myoblast fusionBranched actin polymerizationPodosome-like structuresF-actin polymerizationF-actin distributionFormation of multinucleated muscle cellsArp2/3 regulatorsBranched actinActin regulatorsActin structuresDynamic filopodiaActin filamentsMutant alleles