Feedback Inhibition of the epithelial Na+ channel (ENaC): in vitro vs. in vivo
Patel A, Frindt G, Deng S, Palmer L. Feedback Inhibition of the epithelial Na+ channel (ENaC): in vitro vs. in vivo. The FASEB Journal 2012, 26: 867.12-867.12. DOI: 10.1096/fasebj.26.1_supplement.867.12.Peer-Reviewed Original ResearchTwo-electrode voltage clampENaC-expressing oocytesCell surface expressionI NaENaC expressionCell surface expression of ENaCInhibition of ENaCAmiloride-sensitive currentsEpithelial Na+ channelExpression of ENaCCell surfaceFeedback inhibitionIn vivo protocolsNa+ channelsENaCPatch clampVoltage clampInvestigated in vitroRatsOocytesSplit-openOvernight incubationIn vitroHours incubationInhibition