Changing pattern of expression of the epidermal growth factor receptor and transforming growth factor alpha in the progression of prostatic neoplasms.
Scher H, Sarkis A, Reuter V, Cohen D, Netto G, Petrylak D, Lianes P, Fuks Z, Mendelsohn J, Cordon-Cardo C. Changing pattern of expression of the epidermal growth factor receptor and transforming growth factor alpha in the progression of prostatic neoplasms. Clinical Cancer Research 1995, 1: 545-50. PMID: 9816014.Peer-Reviewed Original ResearchConceptsEpidermal growth factor receptorTGF-alpha expressionTGF-alphaGrowth factor alphaGrowth factor receptorFactor alphaPattern of expressionEpithelial cellsProstate cancer cell growthAutocrine/paracrine interactionsStaining patternRole of EGFRAndrogen-independent tumorsFactor receptorUntreated primary tumorsMalignant prostate epithelial cellsAndrogen-independent diseaseImmunohistochemical staining patternHomogeneous staining patternProstate cancer progressionMalignant epithelial cellsPrimary prostate tumorsCancer cell growthAndrogen-independent conditionGrowth factor pathways