2019
MP64-05 PREDICTING VESICOURETERAL REFLUX RESOLUTION: ANALYSIS OF VUR INDEX, DISTAL URETERAL DIAMETER RATIO, AND INTERNATIONAL REFLUX GRADE
Wu* C, Kirsch A, Leong T, Cooper C, Arlen A. MP64-05 PREDICTING VESICOURETERAL REFLUX RESOLUTION: ANALYSIS OF VUR INDEX, DISTAL URETERAL DIAMETER RATIO, AND INTERNATIONAL REFLUX GRADE. Journal Of Urology 2019, 201 DOI: 10.1097/01.ju.0000556897.02462.af.Peer-Reviewed Original Research
2017
Endoscopic Treatment of Vesicoureteral Reflux
Arlen A, Kirsch A. Endoscopic Treatment of Vesicoureteral Reflux. Current Bladder Dysfunction Reports 2017, 12: 217-224. DOI: 10.1007/s11884-017-0431-6.Peer-Reviewed Original ResearchPrimary vesicoureteral refluxVesicoureteral refluxRenal scarringClinical courseRecurrent febrile urinary tract infectionsFebrile urinary tract infectionLaparoscopic/robotic approachChild's clinical courseContinuous antibiotic prophylaxisUltimate success rateUrinary tract infectionMajority of childrenInvasive surgical proceduresAntibiotic prophylaxisEfficacy rateEndoscopic injectionPersistent refluxReflux gradeTract infectionsEndoscopic correctionEndoscopic treatmentSurgical repairRecurrent infectionsSurgical interventionSurgical correctionValidation of the ureteral diameter ratio for predicting early spontaneous resolution of primary vesicoureteral reflux
Arlen AM, Kirsch AJ, Leong T, Cooper CS. Validation of the ureteral diameter ratio for predicting early spontaneous resolution of primary vesicoureteral reflux. Journal Of Pediatric Urology 2017, 13: 383.e1-383.e6. PMID: 28256423, DOI: 10.1016/j.jpurol.2017.01.012.Peer-Reviewed Original ResearchConceptsPrimary vesicoureteral refluxUreteral diameter ratioVesicoureteral refluxReflux gradeSpontaneous resolutionVUR gradeMultivariable modelUreteral diameterDistal ureteral diameter ratioGrade of VURLargest ureteral diameterPersistent vesicoureteral refluxVesicoureteral reflux gradeGrade of refluxImportant prognostic factorSpontaneous resolution rateValuable prognostic informationL3 vertebral bodyUnit increaseExternal validation studyHighest likelihood ratioVUR timingPersistent diseasePrimary outcomePrognostic factors
2016
Vesicoureteral Reflux Index: Predicting Primary Vesicoureteral Reflux Resolution in Children Diagnosed after Age 24 Months
Garcia-Roig M, Ridley DE, McCracken C, Arlen AM, Cooper CS, Kirsch AJ. Vesicoureteral Reflux Index: Predicting Primary Vesicoureteral Reflux Resolution in Children Diagnosed after Age 24 Months. Journal Of Urology 2016, 197: 1150-1157. PMID: 27939835, DOI: 10.1016/j.juro.2016.12.008.Peer-Reviewed Original ResearchConceptsResolution/improvementAge 24 monthsReflux indexIndex scoreReflux gradeUreteral abnormalitiesImprovement/resolutionVesicoureteral reflux gradeGrade of improvementHigh grade refluxPrimary vesicoureteral refluxMedian resolution timesProportional subdistribution hazards modelSubdistribution hazard modelVesicoureteral reflux resolutionGrade refluxDifferent time pointsSD ageLatest followupVesicoureteral refluxReflux resolutionVoiding cystourethrogramFemale genderInclusion criteriaDiagnosis increasesInter-rater reliability of distal ureteral diameter ratio compared to grade of VUR
Swanton A, Arlen A, Alexander S, Kieran K, Storm D, Cooper C. Inter-rater reliability of distal ureteral diameter ratio compared to grade of VUR. Journal Of Pediatric Urology 2016, 13: 207.e1-207.e5. PMID: 28089295, DOI: 10.1016/j.jpurol.2016.10.021.Peer-Reviewed Original ResearchConceptsUreteral diameter ratioDistal ureteral diameter ratioVesicoureteral refluxVUR gradeInter-rater reliabilityReflux gradePediatric urologistsGrade of VURGrading of VURLargest ureteral diameterHigh grade refluxImportant prognostic factorPrimary vesicoureteral refluxConfidence intervalsSignificant inter-rater variabilityGood inter-rater reliabilityPrognostic factorsClinical courseClinical outcomesPredictive factorsRenal unitsUreteral diameterInter-rater agreementSpontaneous resolutionBlinded fashion
2014
Bladder Volume at Onset of Vesicoureteral Reflux is an Independent Risk Factor for Breakthrough Febrile Urinary Tract Infection
Alexander S, Arlen A, Storm D, Kieran K, Cooper C. Bladder Volume at Onset of Vesicoureteral Reflux is an Independent Risk Factor for Breakthrough Febrile Urinary Tract Infection. Journal Of Urology 2014, 193: 1342-1346. PMID: 25305355, DOI: 10.1016/j.juro.2014.10.002.Peer-Reviewed Original ResearchConceptsBreakthrough febrile urinary tract infectionFebrile urinary tract infectionUrinary tract infectionOnset of refluxBladder-bowel dysfunctionRisk of pyelonephritisTract infectionsVesicoureteral refluxBladder volumeReflux gradeRecurrent febrile urinary tract infectionsMedian bladder volumeIndependent risk factorAdditional prognostic informationIdentification of childrenDuration of exposureReflux onsetBladder capacityMedian followupSD agePrognostic informationRisk factorsMultivariate analysisClinical decisionInfection