2017
Endoscopic Treatment of Vesicoureteral Reflux
Arlen A, Kirsch A. Endoscopic Treatment of Vesicoureteral Reflux. Current Bladder Dysfunction Reports 2017, 12: 217-224. DOI: 10.1007/s11884-017-0431-6.Peer-Reviewed Original ResearchPrimary vesicoureteral refluxVesicoureteral refluxRenal scarringClinical courseRecurrent febrile urinary tract infectionsFebrile urinary tract infectionLaparoscopic/robotic approachChild's clinical courseContinuous antibiotic prophylaxisUltimate success rateUrinary tract infectionMajority of childrenInvasive surgical proceduresAntibiotic prophylaxisEfficacy rateEndoscopic injectionPersistent refluxReflux gradeTract infectionsEndoscopic correctionEndoscopic treatmentSurgical repairRecurrent infectionsSurgical interventionSurgical correction
2016
Vesicoureteral Reflux
Arlen A, Cooper C. Vesicoureteral Reflux. 2016, 95-113. DOI: 10.1007/978-3-319-29219-9_6.Peer-Reviewed Original ResearchUrinary tract infectionVesicoureteral refluxSurgical correctionRecurrent febrile urinary tract infectionsFebrile urinary tract infectionLaparoscopic/robotic approachContinuous antibiotic prophylaxisMorbidity of treatmentRenal cortical scarringUpper urinary tractAntibiotic prophylaxisCortical scarringRenal injuryTract infectionsUrinary tractSpontaneous resolutionFurther infectionRobotic approachChildren's riskRetrograde flowInfectionRefluxParental preferencesRiskProphylaxisComputer model predicting breakthrough febrile urinary tract infection in children with primary vesicoureteral reflux
Arlen AM, Alexander SE, Wald M, Cooper CS. Computer model predicting breakthrough febrile urinary tract infection in children with primary vesicoureteral reflux. Journal Of Pediatric Urology 2016, 12: 288.e1-288.e5. PMID: 27072485, DOI: 10.1016/j.jpurol.2016.03.005.Peer-Reviewed Original ResearchConceptsBreakthrough febrile urinary tract infectionFebrile urinary tract infectionPrimary vesicoureteral refluxBladder-bowel dysfunctionOnset of VURUrinary tract infectionVesicoureteral refluxLow bladder volumesBladder volumeUTI historyTract infectionsPrognostic calculatorSpontaneous resolutionRecurrent febrile urinary tract infectionsCorrect vesicoureteral refluxRecurrent febrile infectionsRenal parenchymal scarringIndividual child's riskCharacteristic curve areaParenchymal scarringVCUG findingsRenal scarringPatient demographicsVUR gradeFebrile infections
2015
Complications of antireflux surgery
Arlen A, Caldamone A, Kirsch A. Complications of antireflux surgery. 2015, 87-95. DOI: 10.1002/9781118473382.ch10.Peer-Reviewed Original ResearchFebrile urinary tract infectionUrinary tract infectionVesicoureteral refluxPersistent refluxTract infectionsRecurrent febrile urinary tract infectionsContinuous antibiotic prophylaxisUpper urinary tractAntibiotic prophylaxisRecurrent pyelonephritisAntireflux surgeryRenal scarringEndoscopic treatmentSurgical managementUreteral reimplantationBladder pathologySurgical interventionUreteral obstructionUrinary tractOutpatient procedureSurgical correctionUrologic diagnosisHigh success rateOptimal managementRobotic approach
2014
Bladder Volume at Onset of Vesicoureteral Reflux is an Independent Risk Factor for Breakthrough Febrile Urinary Tract Infection
Alexander S, Arlen A, Storm D, Kieran K, Cooper C. Bladder Volume at Onset of Vesicoureteral Reflux is an Independent Risk Factor for Breakthrough Febrile Urinary Tract Infection. Journal Of Urology 2014, 193: 1342-1346. PMID: 25305355, DOI: 10.1016/j.juro.2014.10.002.Peer-Reviewed Original ResearchConceptsBreakthrough febrile urinary tract infectionFebrile urinary tract infectionUrinary tract infectionOnset of refluxBladder-bowel dysfunctionRisk of pyelonephritisTract infectionsVesicoureteral refluxBladder volumeReflux gradeRecurrent febrile urinary tract infectionsMedian bladder volumeIndependent risk factorAdditional prognostic informationIdentification of childrenDuration of exposureReflux onsetBladder capacityMedian followupSD agePrognostic informationRisk factorsMultivariate analysisClinical decisionInfection
2013
Endoscopic Injection Techniques for Vesicoureteral Reflux
Arlen A, Scherz H, Kirsch A. Endoscopic Injection Techniques for Vesicoureteral Reflux. 2013, 207-216. DOI: 10.1007/978-1-4471-5394-8_22.Peer-Reviewed Original ResearchVesicoureteral refluxRecurrent febrile urinary tract infectionsFebrile urinary tract infectionLaparoscopic/robotic approachContinuous antibiotic prophylaxisUrinary tract infectionUpper urinary tractEndoscopic injection techniqueAntibiotic prophylaxisUreteral hydrodistentionRenal scarringPersistent refluxTract infectionsEndoscopic treatmentUreteral reimplantationSurgical interventionTransurethral injectionUrinary tractOutpatient procedureSubmucosal injectionSurgical correctionUreteral orificeUrologic diagnosisDecreased morbidityIntraluminal injection