Joseph G. Cardinale, MD

Associate Professor of Clinical Therapeutic Radiology; Associate Chief for Network and Outreach for Radiation Oncology; Associate Chief and Medical Director for Griffin Hospital for Radiation Oncology

Departments & Organizations

Therapeutic Radiology: Prostate & Genitourinary Radiotherapy

Yale Medicine


Joseph Cardinale, MD, a therapeutic radiologist, prides himself on giving individualized attention to patients in his care. “I was attracted to radiation oncology as a specialty because I am able to combine my clinical interests with emotional support for the many people that I have cared for over the years,” he says.

Dr. Cardinale cares for patients with urologic and prostate cancers at Smilow Cancer Hospital at Yale New Haven and at Griffin Hospital, where he is medical director of radiation oncology. With over 30 years of specializing in urologic malignancies, he treats cancer using a variety of techniques, including radiosurgical techniques, brachytherapy, and intensity modulated radiation therapy (IMRT), a radiation delivery system used in the treatment of difficult-to-reach tumors.

“The explosion of new techniques in radiation oncology, as well as drug therapy, has enabled us to treat patients effectively with few side effects,” explains Dr. Cardinale. “I am hopeful that these treatments can help people get back to a normal life with minimal interruptions.” 

At Yale Medicine, Dr. Cardinale has developed a program for prostate cancer and does outreach and screening work for the medically underserved in the local area. An associate clinical professor of therapeutic radiology at Yale School of Medicine, he also conducts clinical research in hopes of finding new cancer treatments. “I am motivated to find ways to treat cancer that do not involve the removal of affected organs, including the prostate in prostate cancer and the bladder in bladder cancer,” he says.

Education & Training

MD New York Medical College (1980)
BS Manhattan College (1976)
Residency Yale-New Haven Hospital
Board Certification AB of Radiology, Therapeutic Radiology (1984)

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Contact Info

Joseph G. Cardinale, MD
Patient Care Locations
Yale Therapeutic RadiologySmilow Cancer Care - Hamden
2080 Whitney Avenue

Hamden, CT 06518
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Yale Therapeutic RadiologyGriffin Health Radiation Oncology
350 Seymour Avenue

Derby, CT 06418
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Office Location
Yale New Haven Hospital
20 York Street, Ste CB 328

New Haven, CT 06510
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Mailing Address
Therapeutic RadiologyPO Box 208040
New Haven, CT 06520-8040