2021
Male Sex Is Associated With Higher Rates of Liver‐Related Mortality in Primary Biliary Cholangitis and Cirrhosis
John BV, Aitcheson G, Schwartz KB, Khakoo NS, Dahman B, Deng Y, Goldberg D, Martin P, Taddei T, Levy C, Kaplan DE. Male Sex Is Associated With Higher Rates of Liver‐Related Mortality in Primary Biliary Cholangitis and Cirrhosis. Hepatology 2021, 74: 879-891. PMID: 33636012, DOI: 10.1002/hep.31776.Peer-Reviewed Original ResearchConceptsPrimary biliary cholangitisLiver-related deathHepatocellular carcinomaBiliary cholangitisMale sexTime-updated Cox proportional hazards modelsCox proportional hazards modelUrsodeoxycholic acid responseLiver-related mortalityHigher unadjusted ratesRisk of deathVeterans Health AdministrationProportional hazards modelAssociation of sexImpact of sexPBC cirrhosisMale patientsUnadjusted ratesWorse outcomesTotal bilirubinCirrhosisLarge cohortHigh riskHazards modelTransplantation
2019
Analysis of weekend effect in severe acute liver injury: A nationwide database study
Do A, Ilagan‐Ying Y, Taddei TH. Analysis of weekend effect in severe acute liver injury: A nationwide database study. Health Science Reports 2019, 3: e139. PMID: 32166187, PMCID: PMC7060892, DOI: 10.1002/hsr2.139.Peer-Reviewed Original ResearchSevere acute liver injuryAcute liver injuryHospital mortalityWeekend admissionFull model approachLiver injuryTimely managementLarge national inpatient databaseNational inpatient databaseNationwide database studyHospital-level characteristicsRevision diagnosis codesMultiple logistic regressionSignificant mortality differenceLarger hospital sizeComplete covariate dataHospital-level dataEligible hospitalizationsAdmission dayPayer databasePrimary outcomeHispanic raceMale sexPoor outcomeInpatient Database