2014
Hormonal Changes During Menopause and the Impact on Fluid Regulation
Stachenfeld NS. Hormonal Changes During Menopause and the Impact on Fluid Regulation. Reproductive Sciences 2014, 21: 555-561. PMID: 24492487, PMCID: PMC3984489, DOI: 10.1177/1933719113518992.Peer-Reviewed Original ResearchConceptsHormone therapySodium retentionMenopausal womenFluid regulationCardiovascular functionAldosterone-mediated sodium retentionRisk of hyponatremiaBlood pressure responseFemale reproductive hormonesFluid-regulating hormonesBody fluid volumeRisk of dehydrationBody fluid regulationEstrogen therapyHypervolemic hyponatremiaCardiovascular riskEstradiol effectsSodium loadProgesterone exposureMineralocorticoid receptorProgestogen exposureReproductive hormonesReproductive surgeryHormonal changesDistal tubules
2012
Blood pressure and water regulation: understanding sex hormone effects within and between men and women
Wenner MM, Stachenfeld NS. Blood pressure and water regulation: understanding sex hormone effects within and between men and women. The Journal Of Physiology 2012, 590: 5949-5961. PMID: 23027816, PMCID: PMC3530109, DOI: 10.1113/jphysiol.2012.236752.Peer-Reviewed Original ResearchConceptsOvarian hormone exposureBlood pressureHormone exposureHormone effectsYoung womenOvarian hormone effectsSuppress reproductive functionBlood pressure controlFirst-line treatmentSex differencesEffects of estrogenPlasma volume expansionCause of deathSex hormone effectsBody fluid regulationGreater morbidityHealthy womenLine treatmentOvarian hormonesMenopausal womenBody water balanceOrthostatic toleranceProgesterone exposureMenstrual cycleHormone administration
2008
Sex Hormone Effects on Body Fluid Regulation
Stachenfeld NS. Sex Hormone Effects on Body Fluid Regulation. Exercise And Sport Sciences Reviews 2008, 36: 152-159. PMID: 18580296, PMCID: PMC2849969, DOI: 10.1097/jes.0b013e31817be928.Peer-Reviewed Original ResearchConceptsFluid regulationBody fluid regulationTotal body waterArginine vasopressinHormone effectsYoung womenPlasma volumeBody waterEstradiol
1999
Effects of oral contraceptives on body fluid regulation
Stachenfeld N, Silva C, Keefe D, Kokoszka C, Nadel E. Effects of oral contraceptives on body fluid regulation. Journal Of Applied Physiology 1999, 87: 1016-1025. PMID: 10484572, DOI: 10.1152/jappl.1999.87.3.1016.Peer-Reviewed Original ResearchConceptsBody fluid regulationLuteal phaseHighest plasma estradiol concentrationFluid regulationOral contraceptive administrationBody fluid retentionPlasma estradiol concentrationsMidluteal menstrual phasesBody fluid balanceArginine vasopressin concentrationBasal plasma osmolalityExercise dehydrationOral contraceptivesContraceptive administrationBody water balanceFluid retentionFollicular phaseEstradiol concentrationsAVP releaseMenstrual phaseFluid balanceVasopressin concentrationCrossover designThirst stimulationPlasma osmolality