2022
Sex differences in arterial identity correlate with neointimal hyperplasia after balloon injury
Gao M, Gao X, Taniguchi R, Brahmandam A, Matsubara Y, Liu J, Liu H, Zhang W, Dardik A. Sex differences in arterial identity correlate with neointimal hyperplasia after balloon injury. Molecular Biology Reports 2022, 49: 8301-8315. PMID: 35715609, PMCID: PMC9463237, DOI: 10.1007/s11033-022-07644-2.Peer-Reviewed Original ResearchConceptsBalloon injuryFemale ratsArterial remodelingNeointimal proliferationCarotid arteryNeointimal thicknessSex differencesLeft common carotid arteryAtherosclerotic arterial diseaseSmooth muscle cell proliferationRight carotid arteryCarotid balloon injuryMale Sprague-DawleyCommon carotid arteryBaseline sex differencesMuscle cell proliferationErythropoietin-producing hepatocellular (Eph) receptorsBackgroundEndovascular treatmentArterial diseaseArterial injuryClinical outcomesSex hormonesUninjured controlsArterial identitySprague-Dawley
2021
Roles of MicroRNAs in Peripheral Artery In-Stent Restenosis after Endovascular Treatment
Wang M, Zhang W, Zhang L, Wang L, Li J, Shu C, Li X. Roles of MicroRNAs in Peripheral Artery In-Stent Restenosis after Endovascular Treatment. BioMed Research International 2021, 2021: 9935671. PMID: 34368362, PMCID: PMC8337102, DOI: 10.1155/2021/9935671.Peer-Reviewed Original ResearchConceptsPercutaneous transluminal angioplastyEndovascular repairStent restenosisPeripheral arterial diseaseNovel therapeutic targetPotential therapeutic strategyMajor pathological processesTransluminal angioplastyArterial diseaseEndovascular treatmentLimited complicationsPeripheral arteriesStent implantationEndothelial denudationInflammatory responseClinical studiesNeointimal hyperplasiaTherapeutic strategiesRole of microRNAsTherapeutic targetRestenosisPathological processesLong-term successRole of miRNAsUnderlying mechanism