2012
Optimal noise reduction in 3D reconstructions of single particles using a volume-normalized filter
Sindelar CV, Grigorieff N. Optimal noise reduction in 3D reconstructions of single particles using a volume-normalized filter. Journal Of Structural Biology 2012, 180: 26-38. PMID: 22613568, PMCID: PMC3498508, DOI: 10.1016/j.jsb.2012.05.005.Peer-Reviewed Original ResearchConceptsParticle mapsOptimal noise reductionWiener filterError reduction schemeConventional Wiener filterNoise reductionNovel filterInversion methodNew filterHigh noise levelsParticle densityParticle volumeFilterParticlesNoise ratioNoise levelTheoretical analysisSingle particleAccurate implementationSpectral signalsSSNRInterior regionImage dataSignalsFourier inversion method
2011
An adaptation of the Wiener filter suitable for analyzing images of isolated single particles
Sindelar CV, Grigorieff N. An adaptation of the Wiener filter suitable for analyzing images of isolated single particles. Journal Of Structural Biology 2011, 176: 60-74. PMID: 21757012, PMCID: PMC3184790, DOI: 10.1016/j.jsb.2011.06.010.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsCryoelectron MicroscopyFourier AnalysisImage Processing, Computer-AssistedModels, MolecularProtein ConformationSignal-To-Noise RatioConceptsWiener filterConventional Wiener filterCryo-EM applicationsNew filterFourier ring correlationParticle areaEstimation schemeFilterLeast-squares senseEstimation methodNoise ratioSpecific applicationsSingle particleParticlesImage fieldError reductionNumeric testsApplicationsImaging conditionsSimulated dataInput data