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Mehmet Sofuoglu, MD, PhD

Professor of Psychiatry
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Additional Titles

Director of VA New England Mental Illness Research, Education and Clinical Center (MIRECC)

About

Titles

Professor of Psychiatry

Director of VA New England Mental Illness Research, Education and Clinical Center (MIRECC)

Appointments

Other Departments & Organizations

Education & Training

PhD
University of Minnesota (1991)
MD
Hacettepe University Faculty of Medicine (1986)

Research

Overview

Our research is focused on development of novel treatments for substance use disorders and comorbid psychiatric disorders. We conduct both Phase 1 human laboratory studies and outpatient clinical trials testing the efficacy of potential treatments. We are also interested in tobacco regulatory science with a focus on the impact of nicotine and flavors on the appeal and abuse potential of tobacco products. We have developed a novel intravenous nicotine self-administration model which allows examination of both rewarding and aversive effects of nicotine in male and female smokers.
Recent projects include:

  • The reinforcing threshold for intravenous nicotine self-administration in male and female smokers.
  • Individual factors influencing the rewarding effects of nicotine in male and female smokers.
  • Impact of menthol and other flavors on the rewarding effects of nicotine in humans.
  • The potential efficacy of cognitive enhancers as a treatment for substance use disorders.
  • Progesterone as a potential treatment to prevent relapse in women with substance use disorder.


Medical Research Interests

Cocaine-Related Disorders; Psychiatry; Psychiatry and Psychology; Psychotherapy; Substance-Related Disorders; Tobacco

Research at a Glance

Yale Co-Authors

Frequent collaborators of Mehmet Sofuoglu's published research.

Publications

2024

Get In Touch

Contacts

Academic Office Number
Mailing Address

Psychiatry

300 George St

New Haven, CT 06511-

United States

Administrative Support