A rapid, membrane-dependent pathway directs furrow formation through RalA in the early Drosophila embryo
Holly R, Mavor L, Zuo Z, Blankenship J. A rapid, membrane-dependent pathway directs furrow formation through RalA in the early Drosophila embryo. Development 2015, 142: 2316-2328. PMID: 26092850, PMCID: PMC4510590, DOI: 10.1242/dev.120998.Peer-Reviewed Original ResearchConceptsEarly Drosophila embryoDrosophila embryosFurrow formationPlasma membraneRalA functionMembrane trafficking pathwaysEarly syncytial Drosophila embryoExocyst complex subunitsEarly fly embryoSyncytial Drosophila embryosWild-type embryosMyosin II functionF-actin recruitmentExocyst complexExocytic vesiclesMembrane traffickingFly embryoTrafficking pathwaysComplex subunitsFurrow ingressionChromosomal segregationCytoskeletal remodelingCell divisionCytokinetic furrowRalA