Chapter 9 Molecular Control of Endothelial Derived Nitric Oxide A New Paradigm for Endothelial NOS Regulation by Posttranslational Modifications
Gratton J, Fontana J, Sessa W. Chapter 9 Molecular Control of Endothelial Derived Nitric Oxide A New Paradigm for Endothelial NOS Regulation by Posttranslational Modifications. 2000, 157-166. DOI: 10.1016/b978-012370420-7/50010-1.Peer-Reviewed Original ResearchNitric oxideEndothelial NOSVascular remodelingEndothelium-derived relaxing factorsEndothelium-derived nitric oxideEndothelial nitric oxide synthase regulationBlood pressure controlNitric oxide synthase regulationRelaxing factorsVasomotor controlCardiovascular homeostasisNOS isoformsVascular endotheliumVascular biologyNOS regulationPhysiological productionPosttranslational control mechanismsFamily membersAngiogenesisProfound perturbationRemodelingPosttranslational modificationsMolecular controlThrombosisInflammationVasomotor control in arterioles of the mouse cremaster muscle
HUNGERFORD J, SESSA W, SEGAL S. Vasomotor control in arterioles of the mouse cremaster muscle. The FASEB Journal 2000, 14: 197-207. PMID: 10627294, DOI: 10.1096/fasebj.14.1.197.Peer-Reviewed Original ResearchConceptsMouse cremaster muscleVasomotor controlCremaster musclePerivascular sympathetic nerve stimulationAnesthetized C57Bl6 miceMicroiontophoresis of acetylcholineSympathetic nerve stimulationNitro-L-arginineConcentration-dependent vasoconstrictionBlood flow controlCremaster muscle preparationFocal vasoconstrictionVasodilatory responseNerve stimulationTransgenic mouse technologyVasomotor responsesC57BL6 miceCardiovascular functionNormal miceMuscle preparationsArteriolesBiphasic responseIntravital microscopyAcetylcholineVasoconstriction