2001
Computed Tomography of the Head before Lumbar Puncture in Adults with Suspected Meningitis
Hasbun R, Abrahams J, Jekel J, Quagliarello V. Computed Tomography of the Head before Lumbar Puncture in Adults with Suspected Meningitis. New England Journal Of Medicine 2001, 345: 1727-1733. PMID: 11742046, DOI: 10.1056/nejmoa010399.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overBrainBrain DiseasesHeadHumansMeningitisMiddle AgedProspective StudiesRegression AnalysisRisk FactorsSpinal PunctureTomography, X-Ray ComputedConceptsLumbar punctureAbnormal findingsNeurologic abnormalitiesCentral nervous system diseaseAbnormal visual fieldsHealth Stroke ScaleMild mass effectHistory of seizuresUnderwent lumbar punctureNervous system diseasesResults of CTMass effectNegative predictive valueBase lineStroke ScaleClinical characteristicsClinical featuresFacial palsyArm driftCT scanSystem diseasesComputed tomographyPatientsMeningitisPredictive value
1996
Acute meningitis with a negative gram's stain: Clinical and management outcomes in 171 episodes
Elmore J, Horwitz R, Quagliarello V. Acute meningitis with a negative gram's stain: Clinical and management outcomes in 171 episodes. The American Journal Of Medicine 1996, 100: 78-84. PMID: 8579091, DOI: 10.1016/s0002-9343(96)90015-7.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAdolescentAdultAnti-Bacterial AgentsBacteremiaChildCohort StudiesColoring AgentsCommunity-Acquired InfectionsComorbidityDecision MakingFemaleFeverHumansImmunocompromised HostLength of StayLeukocyte CountLyme DiseaseMagnetic Resonance ImagingMaleMeningitis, AsepticMiddle AgedNeckRetrospective StudiesSeasonsSyphilisTomography, X-Ray ComputedTreatment OutcomeConceptsAcute meningitisComorbid diseasesDiagnostic causesExamination findingsCerebrospinal fluid white blood cell countWhite blood cell countCommunity-acquired illnessPhysicians' management decisionsRetrospective cohort studyEmpiric antibiotic therapyBlood cell countNegative Gram stainMagnetic resonance imagingConcurrent comorbid diseasesEmpiric treatmentCohort studyMedian stayNeck stiffnessAntibiotic therapyClinical outcomesParaclinical dataCranial imagingEmergency departmentFrequent findingTreatable disease