2024
Serial direct sodium removal in patients with heart failure and diuretic resistance
Rao V, Ivey‐Miranda J, Cox Z, Moreno‐Villagomez J, Ramos‐Mastache D, Neville D, Balkcom N, Asher J, Bellumkonda L, Bigvava T, Shaburishvili T, Bartunek J, Wilson F, Finkelstein F, Maulion C, Turner J, Testani J. Serial direct sodium removal in patients with heart failure and diuretic resistance. European Journal Of Heart Failure 2024, 26: 1215-1230. PMID: 38556717, DOI: 10.1002/ejhf.3196.Peer-Reviewed Original ResearchConceptsDiuretic resistanceCardiorenal syndromeHeart failureLoop diureticsDiuretic withdrawalHigh-dose loop diureticsN-terminal pro-B-type natriuretic peptidePro-B-type natriuretic peptideGrowth differentiation factor 15Carbohydrate antigen 125Differentiation factor 15Sodium removalRandomized controlled studyCardiorenal parametersDiuretic doseSoluble ST2Natriuretic peptideMedian timeDiuretic responseKidney injuryPeritoneal membraneElectrolyte handlingKidney functionDiureticsInterleukin-6
2019
Biomarkers of Intravascular and Extravascular Volume Overload: Associations with Parameters of Cardio-Renal Dysfunction
Gomez N, Stewart B, Barnett J, Thomas A, Wycallis E, Pattoli M, Struyk G, Fleming J, Shamlian P, Raghavendra P, Mahoney D, Ivey-Miranda J, Griffin M, Rao V, Testani J. Biomarkers of Intravascular and Extravascular Volume Overload: Associations with Parameters of Cardio-Renal Dysfunction. Journal Of Cardiac Failure 2019, 25: s21. DOI: 10.1016/j.cardfail.2019.07.060.Peer-Reviewed Original ResearchIntravascular volume overloadCardio-renal dysfunctionExtravascular volume overloadNT-proBNPCA 125Volume overloadDiuretic efficiencyFluid overloadHeart failureUrinary kidney injury molecule-1Kidney injury molecule-1Higher NT-proBNPLoop diuretic dosePlasma NT-proBNPInjury molecule-1Median NT-proBNPCarbohydrate antigen 125Cardio-renal functionIntravascular fluid overloadExtravascular fluid overloadDiuretic doseIntravascular overloadLower eGFRSodium excretionUrine albumin