2024
A Multi-Site Study to Develop and Validate First Trimester, Circulating Microparticle Biomarkers for Tiered Risk Stratification of Spontaneous Preterm Birth in Nulliparas
Rosenblatt K, Zhang Z, Doss R, Gurnani P, Grobman W, Silver R, Parry S, Reddy U, Cao S, Haas D. A Multi-Site Study to Develop and Validate First Trimester, Circulating Microparticle Biomarkers for Tiered Risk Stratification of Spontaneous Preterm Birth in Nulliparas. American Journal Of Obstetrics And Gynecology 2024 PMID: 38789072, DOI: 10.1016/j.ajog.2024.05.032.Peer-Reviewed Original ResearchIn vitro diagnostic multivariate index assaySpontaneous preterm birthGestational agePreterm birthLow riskModerate riskPrediction of spontaneous preterm birthHR groupRisk ratioHigh riskMonitoring Mothers-to-BeNulliparous Pregnancy Outcomes StudyTrimester of pregnancyMultivariate index assayPregnancy Outcomes StudyNested case-control designStatistically significant differencePregnant patientsWeeks gestationMass spectrometry assayCase-control designRisk stratificationStratify riskMothers-to-beStratification toolAssociation of Mild Iodine Insufficiency during Pregnancy with Child Neurodevelopment in Patients with Subclinical Hypothyroidism or Hypothyroxinemia
Casey B, Mele L, Peaceman A, Varner M, Reddy U, Wapner R, Thorp J, Saade G, Tita A, Rouse D, Sibai B, Costantine M, Mercer B, Caritis S. Association of Mild Iodine Insufficiency during Pregnancy with Child Neurodevelopment in Patients with Subclinical Hypothyroidism or Hypothyroxinemia. American Journal Of Perinatology 2024, 41: e3326-e3332. PMID: 38228158, PMCID: PMC11153033, DOI: 10.1055/s-0043-1778037.Peer-Reviewed Original ResearchUrinary iodine concentrationSubclinical hypothyroidismSubclinical thyroid diseasePregnant patientsIodine statusIodine insufficiencyThyroid diseaseIodine concentrationMaternal urinary iodine concentrationPrimary outcomePlacebo-controlled treatment trialMaternal iodine statusMild iodine insufficiencyIntelligence quotientFull-scale intelligence quotientYears of ageDifferential Ability Scales-IISingleton gestationsDouble-maskedIdentical placeboLevothyroxine replacementWeeks gestationMaternal urineThyroid screeningSerum thyrotropin
2023
Continuous non-invasive hemodynamic monitoring in early onset severe preeclampsia
Ackerman-Banks C, Bhinder J, Eder M, Heerdt P, Sugeng L, Testani J, Alian A, Lipkind H, Velazquez E, Reddy U, Chou J. Continuous non-invasive hemodynamic monitoring in early onset severe preeclampsia. Pregnancy Hypertension 2023, 34: 27-32. PMID: 37783090, DOI: 10.1016/j.preghy.2023.09.003.Peer-Reviewed Original ResearchConceptsTotal peripheral resistanceCardiac outputSevere preeclampsiaHemodynamic monitoringEarly-onset severe preeclampsiaProspective observational studyOnset severe preeclampsiaContinuous hemodynamic monitoringNon-invasive hemodynamic monitoringEarly preeclampsiaPregnant patientsPeripheral resistanceObservational studyPreeclampsiaLow mean biasDays postpartumNICOMModerate correlationPoor correlationMean biasAntepartumPatients
2019
Early Preterm Preeclampsia Outcomes by Intended Mode of Delivery
Coviello E, Iqbal S, Grantz K, Huang C, Landy H, Reddy U. Early Preterm Preeclampsia Outcomes by Intended Mode of Delivery. Obstetric Anesthesia Digest 2019, 39: 187-188. DOI: 10.1097/01.aoa.0000603672.77426.4d.Peer-Reviewed Original ResearchSevere featuresEarly preterm deliveryEarly preterm preeclampsiaEarly preterm birthElevated liver enzymesSyndrome of hemolysisIntended modePreeclampsia outcomesNeonatal outcomesPregnant patientsPreterm deliveryPreterm preeclampsiaPreterm birthLow plateletsMaternal mortalityLiver enzymesPaucity of studiesPreeclampsiaOutcomesDeliveryEclampsiaMorbidityPatientsPregnancySyndrome