2024
Pregnancy Outcomes in Patients With Hepatitis C Virus Infection
Hughes B, Sandoval G, Saade G, Clifton R, Reddy U, Bartholomew A, Salazar A, Chien E, Tita A, Thorp J, Metz T, Wapner R, Sabharwal V, Simhan H, Swamy G, Heyborne K, Sibai B, Grobman W, El-Sayed Y, Casey B, Parry S, Macones G, Prasad M. Pregnancy Outcomes in Patients With Hepatitis C Virus Infection. Obstetrics And Gynecology 2024, 144: 501-506. PMID: 39173174, DOI: 10.1097/aog.0000000000005703.Peer-Reviewed Original ResearchSmall-for-gestational-ageHepatitis C virusHepatitis C virus infectionCase groupIncreased oddsPreterm birthNeonatal infectionGestational diabetesMaternal outcomesHCV infectionBirth weightSmall-for-gestational-age birth weightAdmission to neonatal intensive careControl groupIncreased odds of preterm birthPositive hepatitis C virusOdds of NICU admissionOutcomes associated with pregnancyMulticenter prospective cohort studyOdds of preterm birthMaternal HCV infectionMaternal medical comorbiditiesSGA birth weightAdverse maternal outcomesC virus infection
2023
Maternal Morbidity Risk Factors in Nulliparas
Merriam A, Metz T, Allshouse A, Silver R, Haas D, Grobman W, Simhan H, Wapner R, Wing D, Mercer B, Parry S, Reddy U, Investigators +. Maternal Morbidity Risk Factors in Nulliparas. American Journal Of Perinatology 2023, 41: e1878-e1884. PMID: 37150178, DOI: 10.1055/a-2088-2586.Peer-Reviewed Original ResearchVenous thromboembolic eventsSelf-identified black raceComposite maternal morbidityPrimary maternal outcomeSevere maternal morbidityMaternal morbidityChronic kidney diseaseBlack raceRisk factorsChronic hypertensionHypertensive disordersMaternal outcomesPregestational diabetesKidney diseaseMedical conditionsMulticenter prospective observational cohortPrepregnancy body mass indexPreexisting medical comorbiditiesPrior obstetric historyProspective observational cohortMorbidity risk factorsBody mass indexMultiple risk factorsDays of deliveryLog-binomial regressionHypertension in Pregnancy and Adverse Outcomes Among Low-risk Nulliparous Women Expectantly Managed at or After 39 weeks: A Secondary Analysis of a Randomized Controlled Trial
Bartal M, Premkumar A, Rice M, Reddy U, Tita A, Silver R, El-Sayed Y, Wapner R, Rouse D, Saade G, Thorp J, Constantine M, Chien E, Casey B, Srinivas S, Swamy G, Simhan H. Hypertension in Pregnancy and Adverse Outcomes Among Low-risk Nulliparous Women Expectantly Managed at or After 39 weeks: A Secondary Analysis of a Randomized Controlled Trial. Obstetric Anesthesia Digest 2023, 43: 82-82. DOI: 10.1097/01.aoa.0000927856.60760.92.Peer-Reviewed Original ResearchLow-risk patientsLow-risk nulliparous womenHypertensive disordersMaternal morbidityMaternal outcomesNulliparous womenControlled TrialsWeeks' gestationAdverse outcomesLower riskSecondary analysisPregnancyPatientsHDPOutcomesRecent studiesHypertensionMorbidityGestationMortalityPrevalenceTrialsWeeksWomen
2022
Treatment for Mild Chronic Hypertension During Pregnancy
Tita A, Szychowski J, Boggess K, Dugoff L, Sibai B, Lawrence K, Hughes B, Bell J, Aagaard K, Edwards R, Gibson K, Haas D, Plante L, Metz T, Casey B, Esplin S, Longo S, Hoffman M, Saade G, Hoppe K, Foroutan J, Tuuli M, Owens M, Simhan H, Frey H, Rosen T, Palatnik A, Baker S, August P, Reddy U, Kinzler W, Su E, Krishna I, Nguyen N, Norton M, Skupski D, El-Sayed Y, Ogunyemi D, Galis Z, Harper L, Ambalavanan N, Geller N, Oparil S, Cutter G, Andrews W. Treatment for Mild Chronic Hypertension During Pregnancy. Obstetrical & Gynecological Survey 2022, 77: 634-636. DOI: 10.1097/01.ogx.0000899456.24100.71.Peer-Reviewed Original ResearchHypertension During PregnancyAcute kidney injuryAdverse neonatal outcomesChronic hypertensionKidney injuryMaternal outcomesNeonatal outcomesPlacental abruptionPreterm birthHeart failureMaternal deathsGestational agePerinatal deathPulmonary edemaPregnancyBlack womenDeathOutcomesHypertensionAbruptionPreeclampsiaEdemaInjuryStrokeWomenHypertension in pregnancy and adverse outcomes among low‐risk nulliparous women expectantly managed at or after 39 weeks: a secondary analysis of a randomised controlled trial
Bartal M, Premkumar A, Rice M, Reddy U, Tita ATN, Silver RM, El‐Sayed Y, Wapner R, Rouse DJ, Saade GR, Thorp JM, Costantine M, Chien EK, Casey BM, Srinivas SK, Swamy GK, Simhan HN, Health H. Hypertension in pregnancy and adverse outcomes among low‐risk nulliparous women expectantly managed at or after 39 weeks: a secondary analysis of a randomised controlled trial. BJOG An International Journal Of Obstetrics & Gynaecology 2022, 129: 1396-1403. PMID: 34927787, PMCID: PMC9207156, DOI: 10.1111/1471-0528.17059.Peer-Reviewed Original ResearchConceptsAdverse maternal outcomesLow-risk nulliparous womenHypertensive disordersMaternal outcomesSecondary outcomesNulliparous womenAdverse outcomesComposite adverse maternal outcomeIntensive care unit admissionSecondary analysisCare unit admissionSevere neonatal complicationsWeeks of gestationMode of deliveryNulliparous individualsMaternal compositeNeonatal complicationsPerinatal compositePostpartum infectionUnit admissionCaesarean deliveryExpectant managementPlacental abruptionVenous thromboembolismGestational age
2021
Maternal and Neonatal Outcomes in Nulliparous Participants Undergoing Labor Induction by Cervical Ripening Method
Andrikopoulou M, Bushman E, Rice M, Grobman W, Reddy U, Silver R, El-Sayed Y, Rouse D, Saade G, Thorp J, Chauhan S, Costantine M, Chien E, Casey B, Srinivas S, Swamy G, Simhan H. Maternal and Neonatal Outcomes in Nulliparous Participants Undergoing Labor Induction by Cervical Ripening Method. American Journal Of Perinatology 2021, 40: 1061-1070. PMID: 34352922, PMCID: PMC8817048, DOI: 10.1055/s-0041-1732379.Peer-Reviewed Original ResearchConceptsAdverse neonatal outcomesCervical ripeningNeonatal outcomesLabor inductionNulliparous participantsComposite outcomeAdverse maternal outcomesCervical ripening methodsMaternal composite outcomeNeonatal composite outcomeLow-risk womenLength of laborConcurrent oxytocinCoprimary outcomesNeonatal compositeExpectant managementMaternal outcomesCesarean deliverySecondary outcomesFetal demisePatient characteristicsMultivariable analysisCervical dilationLower riskSecondary analysisMaternal outcomes and risk factors for COVID-19 severity among pregnant women
Vouga M, Favre G, Martinez-Perez O, Pomar L, Acebal LF, Abascal-Saiz A, Hernandez MRV, Hcini N, Lambert V, Carles G, Sichitiu J, Salomon L, Stirnemann J, Ville Y, de Tejada BM, Goncé A, Hawkins-Villarreal A, Castillo K, Solsona EG, Trigo L, Cleary B, Geary M, Bartels H, Al-Kharouf F, Malone F, Higgins M, Keating N, Knowles S, Poncelet C, Ribeiro-do-Valle CC, Surita F, Dantas-Silva A, Borrelli C, Luz AG, Fuenzalida J, Carvajal J, Canales MG, Hernandez O, Grechukhina O, Ko AI, Reddy U, Figueiredo R, Moucho M, Pinto PV, De Luca C, De Santis M, de Campos DA, Martins I, Garabedian C, Subtil D, Bohrer B, Da Rocha Oppermann ML, Wender MCO, Schuler-Faccini L, Sanseverino MTV, Giugliani C, Friedrich L, Scherer MH, Mottet N, Ducarme G, Pelerin H, Moreau C, Breton B, Quibel T, Rozenberg P, Giannoni E, Granado C, Monod C, Mueller D, Hoesli I, Bassler D, Heldstab S, Kölble NO, Sentilhes L, Charvet M, Deprest J, Richter J, Van der Veeken L, Eggel-Hort B, Plantefeve G, Derouich M, Calvache AJN, Lopez-Giron MC, Burgos-Luna JM, Escobar-Vidarte MF, Hecher K, Tallarek AC, Hadar E, Haratz KK, Amikam U, Malinger G, Maymon R, Yogev Y, Schäffer L, Toussaint A, Rossier MC, De Sa RAM, Grawe C, Aebi-Popp K, Radan AP, Raio L, Surbek D, Böckenhoff P, Strizek B, Kaufmann M, Bloch A, Boulvain M, Johann S, Heldstab SA, Bernasconi MT, Grant G, Feki A, Brochut AM, Giral M, Sedille L, Papadia A, Brugger RC, Weber B, Fischer T, Kahlert C, Saines KN, Cambou M, Kanellos P, Chen X, Yin M, Haessig A, Ackermann S, Baud D, Panchaud A. Maternal outcomes and risk factors for COVID-19 severity among pregnant women. Scientific Reports 2021, 11: 13898. PMID: 34230507, PMCID: PMC8260739, DOI: 10.1038/s41598-021-92357-y.Peer-Reviewed Original ResearchConceptsSevere maternal outcomesPregnant womenRisk factorsMaternal outcomesPulmonary comorbiditiesHypertensive disordersNeonatal outcomesSevere complicationsHigh riskSevere acute respiratory syndrome coronavirus 2Severe coronavirus disease-19Severe COVID-19 diseaseAcute respiratory syndrome coronavirus 2Neonatal intensive care unitSARS-CoV-2 infectionRespiratory syndrome coronavirus 2Immediate neonatal outcomeIntensive care unitSyndrome coronavirus 2COVID-19 severityCase-control studyCoronavirus disease-19SARS-CoV-2COVID-19 diseaseMaternal disease
2019
Effect of Treatment of Mild Gestational Diabetes on Long-Term Maternal Outcomes
Casey B, Rice M, Landon M, Varner M, Reddy U, Wapner R, Rouse D, Biggio J, Thorp J, Chien E, Saade G, Peaceman A, Blackwell S, Van Dorsten J. Effect of Treatment of Mild Gestational Diabetes on Long-Term Maternal Outcomes. American Journal Of Perinatology 2019, 37: 475-482. PMID: 30866027, PMCID: PMC6744360, DOI: 10.1055/s-0039-1681058.Peer-Reviewed Original ResearchConceptsMild gestational diabetes mellitusGestational diabetes mellitusBody mass indexMetabolic syndromeIndex pregnancyTreatment of womenSubsequent diabetesLong-term maternal outcomesMaternal body mass indexOral glucose tolerance testMild gestational diabetesFrequency of diabetesHomeostasis model assessmentGlucose tolerance testRisk of diabetesTreatment of diabetesEffect of treatmentRace/ethnicityGestational diabetesLipid panelMaternal outcomesBlood pressureDiabetes mellitusMedical therapyNutritional counseling
2017
Maternal and Neonatal Outcomes by Mode of Delivery in Obese Women With a Previous Cesarean Section [5R]
Coviello E, Clark-Ganheart C, Huang C, Landy H, Iqbal S, Reddy U. Maternal and Neonatal Outcomes by Mode of Delivery in Obese Women With a Previous Cesarean Section [5R]. Obstetrics And Gynecology 2017, 129: 184s. DOI: 10.1097/01.aog.0000514150.02396.7a.Peer-Reviewed Original ResearchPrior cesarean deliveryDVT/PEMode of deliveryMaternal ICU admissionCesarean deliveryNeonatal outcomesObese womenPostpartum hemorrhageICU admissionObesity classDeep vein thrombosis/pulmonary embolismPlanned repeat cesarean deliveryVBAC success ratePrevious cesarean sectionRepeat cesarean deliveryTrial of laborClasses of obesityMultivariable logistic regressionSuccess rateLess womenHypertensive disordersMaternal outcomesSuccessful VBACCesarean sectionPulmonary embolism
2016
Evaluation of Classical Cesarean Delivery Outcomes [20K]
Kawakita T, Reddy U, Landy H, Grantz K, Desale S, Iqbal S. Evaluation of Classical Cesarean Delivery Outcomes [20K]. Obstetrics And Gynecology 2016, 127: 94s. DOI: 10.1097/01.aog.0000483818.16818.99.Peer-Reviewed Original ResearchClassical cesarean deliveryRepeat cesarean deliveryCesarean deliveryAdjusted odds ratioMaternal outcomesMultivariable logistic regression modelComposite maternal outcomeEmergency cesarean deliveryRetrospective cohort studyGestational age groupsLogistic regression modelsCohort studyEarly pretermIntraoperative outcomesMaternal characteristicsOdds ratioInclusion criteriaAge groupsOutcomesP-valueWeeksWomenRegression modelsDeliveryComorbidities