2019
Prognostic Role of Androgen Receptor in Triple Negative Breast Cancer: A Multi-Institutional Study
Bhattarai S, Klimov S, Mittal K, Krishnamurti U, Li X, Oprea-Ilies G, Wetherilt C, Riaz A, Aleskandarany M, Green A, Ellis I, Cantuaria G, Gupta M, Manne U, Agboola J, Baskovich B, Janssen E, Callagy G, Walsh E, Mehta A, Dogra A, Shet T, Gajaria P, Traina T, Nggada H, Omonisi A, Ahmed S, Rakha E, Rida P, Aneja R. Prognostic Role of Androgen Receptor in Triple Negative Breast Cancer: A Multi-Institutional Study. Cancers 2019, 11: 995. PMID: 31319547, PMCID: PMC6678933, DOI: 10.3390/cancers11070995.Peer-Reviewed Original ResearchTriple-negative breast cancerAR-positive triple-negative breast cancerAndrogen receptorAR statusPrognostic roleOverall survivalBetter prognosisBreast cancerAR-positive nucleiPatients' overall survivalReliable prognostic markersNegative breast cancerPotential therapeutic targetMulti-institutional studyAR positivityTNBC patientsPoor prognosisPrognostic valuePrimary tumorPatient prognosisIndian cohortPrognostic markerUK cohortAR antibodyTNBC samples
2016
CCR6 expression in colon cancer is associated with advanced disease and supports epithelial-to-mesenchymal transition
Kapur N, Mir H, Clark III C, Krishnamurti U, Beech D, Lillard J, Singh S. CCR6 expression in colon cancer is associated with advanced disease and supports epithelial-to-mesenchymal transition. British Journal Of Cancer 2016, 114: 1343-1351. PMID: 27149649, PMCID: PMC4984452, DOI: 10.1038/bjc.2016.113.Peer-Reviewed Original ResearchConceptsColon cancerNodal statusCCR6 expressionTherapeutic optionsEMT markersExpression of CCR6Node-positive casesTNM staging systemUndefined molecular mechanismsPotential therapeutic targetNormal adjacent tissuesTissues/cellsMolecular mechanismsIdentification of markersAdjuvant chemotherapyAdvanced diseaseMolecular pathwaysDistant metastasisN-cadherinClinical associationsStaging systemMetastatic casesInvasive potentialΒ-cateninCancer cases