2021
Lung injury in axolotl salamanders induces an organ‐wide proliferation response
Jensen TB, Giunta P, Schultz NG, Griffiths JM, Duerr TJ, Kyeremateng Y, Wong H, Adesina A, Monaghan JR. Lung injury in axolotl salamanders induces an organ‐wide proliferation response. Developmental Dynamics 2021, 250: 866-879. PMID: 33587313, DOI: 10.1002/dvdy.315.Peer-Reviewed Original ResearchConceptsLung regenerationLung massX cranial nervesLung injurySupplemental administrationCranial nervesProliferative responseProliferation responseInjury responseLungInjuryMultiple cell typesMesenchymal cellsNeuregulinAmputationMost tissuesPneumocytesProliferationCell typesResponseAxolotl salamanderCellsNerve
2020
Transcriptional Heterogeneity of Neural Stem Cells during Axolotl Salamander Spinal Cord Regeneration
Monaghan J, Jensen T, Stein D, Mun E, Maden M. Transcriptional Heterogeneity of Neural Stem Cells during Axolotl Salamander Spinal Cord Regeneration. The FASEB Journal 2020, 34: 1-1. DOI: 10.1096/fasebj.2020.34.s1.00360.Peer-Reviewed Original ResearchNeural stem cellsNascent RNA productionRepressive chromatin marksGlobal RNA synthesisProbe setsCell typesGlobal changeHippo-YAP signalingStem cellsStem cell dynamicsChromatin marksNascent RNATranscriptional outputWhole-mount tissuesTranscriptional heterogeneityAxolotl salamanderGlial cell typesGene transcriptionRNA productionFISH probe setsNeural progenitorsMultiplexed fluorescenceRegenerative programNeural differentiationNSC population