Longitudinal hippocampal circuit change differentiates persistence and remission of pediatric posttraumatic stress disorder
George G, Keding T, Heyn S, Herringa R. Longitudinal hippocampal circuit change differentiates persistence and remission of pediatric posttraumatic stress disorder. Depression And Anxiety 2021, 39: 8-18. PMID: 34843625, PMCID: PMC8763137, DOI: 10.1002/da.23229.Peer-Reviewed Original ResearchConceptsPediatric posttraumatic stress disorderFunctional magnetic resonance imagingPosttraumatic stress disorderTD youthHippocampal activationStress disorderFunctional connectivityEmotional processing taskFunctional brain substratesHippocampal functional connectivityFunctional connectivity analysisFunctional brain abnormalitiesPTSD youthEmotion processingThreat stimuliNeutral imagesPediatric PTSDBrain substratesPTSD groupActivation findingsConnectivity analysisProcessing tasksVisual cortexLongitudinal studyYouthNeurobehavioral correlates of impaired emotion recognition in pediatric PTSD
Heyn SA, Schmit C, Keding TJ, Wolf R, Herringa RJ. Neurobehavioral correlates of impaired emotion recognition in pediatric PTSD. Development And Psychopathology 2021, 34: 946-956. PMID: 33487187, PMCID: PMC9717496, DOI: 10.1017/s0954579420001704.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderPediatric posttraumatic stress disorderTD youthFunctional connectivityImplicit emotion processing taskEmotion recognition taskImpaired emotion recognitionFunctional magnetic resonance imagingEmotion processing taskSample of youthNeutral facesAngry expressionsVisual attentionFMRI taskEmotion recognitionNeurobehavioral correlatesStress disorderNeurological substrateRecognition taskProcessing tasksYouth experienceMultimethod approachYouthImpaired abilityThreat recognition