2011
Effect of Treatment Interruption and Intensification of Antiretroviral Therapy on Health-Related Quality of Life in Patients with Advanced HIV
Joyce VR, Barnett PG, Chow A, Bayoumi AM, Griffin SC, Sun H, Holodniy M, Brown ST, Kyriakides TC, Cameron DW, Youle M, Sculpher M, Anis AH, Owens DK. Effect of Treatment Interruption and Intensification of Antiretroviral Therapy on Health-Related Quality of Life in Patients with Advanced HIV. Medical Decision Making 2011, 32: 70-82. PMID: 21383086, DOI: 10.1177/0272989x10397615.Peer-Reviewed Original ResearchConceptsVisual analog scaleHIV patientsART intensificationTreatment interruptionClinical eventsMedical Outcomes Study HIV Health SurveyAdvanced HIV patientsAntiretroviral therapy interruptionMultiple treatment failuresTemporary treatment interruptionAdverse clinical eventsHealth-related qualityStandard ARTHealth Utilities IndexStandard gambleQuality of lifeAdvanced HIVART interruptionInferior HRQoLMDR HIVTherapy interruptionAntiretroviral therapyHIV cohortOpen labelHRQoL scores
2009
Outcomes Following Endovascular vs Open Repair of Abdominal Aortic Aneurysm: A Randomized Trial
Lederle FA, Freischlag JA, Kyriakides TC, Padberg FT, Matsumura JS, Kohler TR, Lin PH, Jean-Claude JM, Cikrit DF, Swanson KM, Peduzzi PN, Group F. Outcomes Following Endovascular vs Open Repair of Abdominal Aortic Aneurysm: A Randomized Trial. JAMA 2009, 302: 1535-1542. PMID: 19826022, DOI: 10.1001/jama.2009.1426.Peer-Reviewed Original ResearchMeSH KeywordsAgedAortic Aneurysm, AbdominalBlood Vessel Prosthesis ImplantationCatheterization, PeripheralErectile DysfunctionFemaleHumansKaplan-Meier EstimateLength of StayMaleMiddle AgedMinimally Invasive Surgical ProceduresMorbidityPostoperative ComplicationsProportional Hazards ModelsQuality of LifeConceptsAbdominal aortic aneurysmOpen repairShort-term outcomesEndovascular repairPerioperative mortalityMajor morbidityAortic aneurysmProcedure failureTherapeutic proceduresIntensive care unit stayLong-term outcome dataVeterans Affairs Medical CenterElective endovascular repairEndovascular repair groupHealth-related qualityTraditional open repairElective AAA repairMedian procedure timeLength of stayMulticenter clinical trialQuality of lifeElective endovascularTransfusion requirementsUnit stayHospital stayQuality of Life of Patients With Advanced HIV/AIDS: Measuring the Impact of Both AIDS-Defining Events and Non-AIDS Serious Adverse Events
Anis AH, Nosyk B, Sun H, Guh DP, Bansback N, Li X, Barnett PG, Joyce V, Swanson KM, Kyriakides TC, Holodniy M, Cameron DW, Brown ST. Quality of Life of Patients With Advanced HIV/AIDS: Measuring the Impact of Both AIDS-Defining Events and Non-AIDS Serious Adverse Events. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2009, 51: 631-639. PMID: 19430303, DOI: 10.1097/qai.0b013e3181a4f00d.Peer-Reviewed Original ResearchConceptsSerious adverse eventsLate-stage HIV/AIDSAdvanced HIV/AIDSHIV/AIDSAdverse eventsMedical Outcomes Study HIV Health SurveyMental health summary scoresEffect of ADEMultidrug-resistant HIVHealth-related qualityHealth summary scoresQuality of lifePatients' HRQOLMultivariate linear regression modelRegular followHRQOL measuresTreatment strategiesEQ-5DHealth SurveyHRQoLImmune diseasesSummary scoresPatientsStudy sample populationAIDSHealth-Related Quality of Life in a Randomized Trial of Antiretroviral Therapy for Advanced HIV Disease
Joyce VR, Barnett PG, Bayoumi AM, Griffin SC, Kyriakides TC, Yu W, Sundaram V, Holodniy M, Brown ST, Cameron W, Youle M, Sculpher M, Anis AH, Owens DK. Health-Related Quality of Life in a Randomized Trial of Antiretroviral Therapy for Advanced HIV Disease. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2009, 50: 27-36. PMID: 19295332, DOI: 10.1097/qai.0b013e31818ce6f3.Peer-Reviewed Original ResearchConceptsHealth Utilities Index Mark 3Treatment-experienced HIV patientsEQ-5DHIV patientsHRQoL scoresClinical variablesMedical Outcomes Study HIV Health SurveyEQ-5D visual analog scaleHealth statusStandard gamblePreference-based health-related qualityAdvanced HIV diseaseBaseline HRQOL scoresConcomitant medication useTreatment-experienced HIVCD4 cell countHIV viral loadHealth-related qualityVisual analog scaleVeterans Affairs hospitalEQ-5D VASCross-sectional studyPreference-based HRQOLQuality of lifeTime trade-off (TTO) technique