2018
Aromatase and estrogen receptor immunoreactivity in the coronary arteries of monkeys and human subjects
Diano S, Horvath TL, Mor G, Register T, Adams M, Harada N, Naftolin F. Aromatase and estrogen receptor immunoreactivity in the coronary arteries of monkeys and human subjects. Menopause The Journal Of The North American Menopause Society 2018, 25: 1201-1207. PMID: 30358714, DOI: 10.1097/gme.0000000000001219.Peer-Reviewed Original ResearchConceptsCoronary arteryEstrogen receptor immunoreactivityAmount of atherosclerosisHuman placental estrogen synthetaseHuman subjectsSmooth muscle cellsPrecursor androgensReceptor immunoreactivityCardioprotective effectsCoronary circulationEstrogen formationEstrogen receptorArteryCardiovascular systemER αMuscle cellsEndothelial cellsEstrogenEstrogen synthetaseMonkeysFirst evidenceSubjectsCellsAtherosclerosisLocal regulation
2013
Role of uncoupling protein 3 in ischemia-reperfusion injury, arrhythmias, and preconditioning
Ozcan C, Palmeri M, Horvath TL, Russell KS, Russell RR. Role of uncoupling protein 3 in ischemia-reperfusion injury, arrhythmias, and preconditioning. AJP Heart And Circulatory Physiology 2013, 304: h1192-h1200. PMID: 23457013, PMCID: PMC3652089, DOI: 10.1152/ajpheart.00592.2012.Peer-Reviewed Original ResearchMeSH KeywordsAdenosine TriphosphateAnimalsArrhythmias, CardiacCarbonyl Cyanide p-TrifluoromethoxyphenylhydrazoneCoronary OcclusionIn Vitro TechniquesIon ChannelsIschemic Preconditioning, MyocardialMaleMiceMice, Inbred C57BLMitochondrial ProteinsMyocardial InfarctionMyocardial Reperfusion InjuryMyocytes, CardiacReactive Oxygen SpeciesUncoupling Protein 2Uncoupling Protein 3Ventricular DysfunctionConceptsIschemia-reperfusion injuryR injuryIschemic preconditioningWT heartsMyocardial energeticsMouse heartsReactive oxygen speciesLeft coronary arteryLeft ventricular functionPostischemic functional recoveryWild-type mouse heartsUncoupling proteinDecreased ATP contentR arrhythmiasLarge infarctsVentricular functionFunctional recoveryWT miceCoronary arteryProtective efficacyCardioprotective efficacyMyocardial vulnerabilityVivo modelInjuryRole of UCPs
1999
Aromatase and Estrogen Receptor Immunoreactivity in the Coronary Arteries of Monkeys and Human Subjects
Diano S, Horvath T, Mor G, Register T, Adams M, Harada N, Naftolin F. Aromatase and Estrogen Receptor Immunoreactivity in the Coronary Arteries of Monkeys and Human Subjects. Menopause The Journal Of The North American Menopause Society 1999, 6: 21-28. PMID: 10100176, DOI: 10.1097/00042192-199906010-00006.Peer-Reviewed Original ResearchConceptsCoronary arteryEstrogen receptor immunoreactivityAmount of atherosclerosisHuman placental estrogen synthetaseHuman subjectsSmooth muscle cellsPrecursor androgensReceptor immunoreactivityCardioprotective effectsCoronary circulationEstrogen formationER alphaEstrogen receptorArteryCardiovascular systemMuscle cellsEndothelial cellsEstrogenEstrogen synthetaseAromataseMonkeysFirst evidenceSubjectsCellsAtherosclerosis