2012
Understanding chronic inflammatory and neuropathic pain
Hughes J, Chessell I, Malamut R, Perkins M, Bačkonja M, Baron R, Farrar J, Field M, Gereau R, Gilron I, McMahon S, Porreca F, Rappaport B, Rice F, Richman L, Segerdahl M, Seminowicz D, Watkins L, Waxman S, Wiech K, Woolf C. Understanding chronic inflammatory and neuropathic pain. Annals Of The New York Academy Of Sciences 2012, 1255: 30-44. PMID: 22564068, DOI: 10.1111/j.1749-6632.2012.06561.x.Peer-Reviewed Original Research
2000
Voltage-gated sodium channels and the molecular pathogenesis of pain: a review.
Waxman SG, Cummins TR, Dib-Hajj SD, Black JA. Voltage-gated sodium channels and the molecular pathogenesis of pain: a review. The Journal Of Rehabilitation Research And Development 2000, 37: 517-28. PMID: 11322150.Peer-Reviewed Original ResearchConceptsVoltage-gated sodium channelsDRG neuronsNervous systemSodium channelsDistinct voltage-gated sodium channelsAction potentialsSpinal sensory neuronsSodium channel expressionSpontaneous action potentialsDifferent sodium channelsSpecific sodium channelsUnderstanding of painHigh-frequency activityInflammatory painPain pathwaysChronic painNociceptive signalsPeripheral nervesSensory neuronsNew therapiesPainChannel expressionMolecular pathogenesisPharmacologic manipulationNeuron cell membrane
1993
Painless aortic dissection presenting as a progressive myelopathy
Holloway S, Fayad P, Kalb R, Guarnaccia J, Waxman S. Painless aortic dissection presenting as a progressive myelopathy. Journal Of The Neurological Sciences 1993, 120: 141-144. PMID: 8138802, DOI: 10.1016/0022-510x(93)90265-z.Peer-Reviewed Original ResearchConceptsPainless aortic dissectionAortic dissectionProgressive myelopathyCentral nervous system ischemiaSpinal cord syndromeThoracic aortic dissectionAbsence of painThoracic vertebral bodyMagnetic resonance imagingTransverse myelopathyCord syndromeNeurologic deficitsNeurologic symptomsIschemic changesEarly recognitionSpinal cordDifferential diagnosisNew therapiesVertebral bodyResonance imagingMyelopathyThoracic vertebraeDissectionPainIschemia