2014
Dysfunction and recovery in demyelinated and dysmyelinated axons
Waxman S. Dysfunction and recovery in demyelinated and dysmyelinated axons. 2014, 457-471. DOI: 10.1017/cbo9780511995583.034.Peer-Reviewed Original ResearchNervous systemNeural repairNormal central nervous systemSpinal cord damageRecovery of functionCentral nervous systemNeuron replacementCerebral palsyCord damageAxonal regenerationNeuronal deathAxon regenerationNeurological rehabilitationBrain disordersCell therapyRehabilitation professionalsRepairRehabilitationBasic scienceStem cell biologyPalsyDysfunctionPathophysiologyInjuryTherapy
2006
Dysfunction and recovery in demyelinated and dysmyelinated axons
Waxman S. Dysfunction and recovery in demyelinated and dysmyelinated axons. 2006, 468-486. DOI: 10.1017/cbo9780511545061.029.Peer-Reviewed Original Research
1991
Lhermitte's sign in a patient with herpes zoster
Vollmer T, Brass L, Waxman S. Lhermitte's sign in a patient with herpes zoster. Journal Of The Neurological Sciences 1991, 106: 153-157. PMID: 1802963, DOI: 10.1016/0022-510x(91)90252-3.Peer-Reviewed Original ResearchNon-synaptic mechanisms of Ca2+-mediated injury in CNS white matter
Waxman S, Ransom B, Stys P. Non-synaptic mechanisms of Ca2+-mediated injury in CNS white matter. Trends In Neurosciences 1991, 14: 461-468. PMID: 1722366, DOI: 10.1016/0166-2236(91)90046-w.Peer-Reviewed Original Research
1987
Physiological effects of 4‐aminopyridine on demyelinated mammalian motor and sensory fibers
Bowe C, Kocsis J, Targ E, Waxman S. Physiological effects of 4‐aminopyridine on demyelinated mammalian motor and sensory fibers. Annals Of Neurology 1987, 22: 264-268. PMID: 2821876, DOI: 10.1002/ana.410220212.Peer-Reviewed Original ResearchConceptsSensory fibersClinical trialsAction potentialsPotassium channel blockadeDorsal root axonsCompound action potentialDorsal spinal rootsSingle action potentialMammalian motorIntrathecal injectionMultiple sclerosisSensory dysfunctionVentral rootsSpinal rootsNeuromuscular disordersSpecific fiber typesElectrophysiological responsesSingle stimulusPhysiological effectsTrialsFiber typesResponseParesthesiaSclerosisDysfunction
1980
Pathophysiology of nerve conduction: relation to diabetic neuropathy.
WAXMAN S. Pathophysiology of nerve conduction: relation to diabetic neuropathy. Annals Of Internal Medicine 1980, 92: 297-301. PMID: 6243892, DOI: 10.7326/0003-4819-92-2-297.Peer-Reviewed Original ResearchConceptsTotal conduction blockProximal-distal gradientClinicopathologic aspectsDiabetic neuropathyClinical deficitsElectrophysiologic variablesNerve diseasePathophysiologic mechanismsNerve conductionConduction blockPathologic basisConduction velocityImpulse conductionTopographic patternsTemporal dispersionNeuropathyNerveDysfunctionPathophysiologyLesionsDisease
1976
Probability of conduction deficit as related to fiber length in random-distribution models of peripheral neuropathies
Waxman S, Brill M, Geschwind N, Sabin T, Lettvin J. Probability of conduction deficit as related to fiber length in random-distribution models of peripheral neuropathies. Journal Of The Neurological Sciences 1976, 29: 39-53. PMID: 181541, DOI: 10.1016/0022-510x(76)90079-4.Peer-Reviewed Original ResearchConceptsPeripheral neuropathyAxonal dysfunctionSensory deficitsDistal sensory deficitsNormal sensory conductionRapid clinical progressionConduction deficitsSensory conductionClinical progressionNerve fibersConduction blockNeuropathyDysfunctionMarked reductionProximodistal gradientPossible correlatesDeficitsSmall increaseParesthesiaeAbnormalitiesProgression
1975
The Interictal Behavior Syndrome of Temporal Lobe Epilepsy
Waxman S, Geschwind N. The Interictal Behavior Syndrome of Temporal Lobe Epilepsy. JAMA Psychiatry 1975, 32: 1580-1586. PMID: 1200777, DOI: 10.1001/archpsyc.1975.01760300118011.Peer-Reviewed Original ResearchConceptsTemporal lobe epilepsyLobe epilepsyInterictal behavior syndromeInterictal spike activityBehavior syndromeGreat diagnostic valuePathophysiologic basisDistinct syndromeManifest seizuresSpike activitySyndromeDiagnostic valueEpilepsyBehavior alterationsAnatomic locusNeural substratesSexual behaviorBehavioral changesBehavioral syndromeBehavior changeUseful modelAlterationsPatientsDysfunctionSeizures
1974
Subacute brain-stem encephalitis
Waxman S, Sabin T, Embree L. Subacute brain-stem encephalitis. Journal Of Neurology Neurosurgery & Psychiatry 1974, 37: 811. PMID: 4854509, PMCID: PMC494788, DOI: 10.1136/jnnp.37.7.811.Peer-Reviewed Original ResearchConceptsPerivascular lymphocytic cuffingBrain stem encephalitisYear old manBrain stem changesMedullary dysfunctionUnderlying malignancyGlial nodulesLymphocytic cuffingLateral gazeMicroglial infiltrationPathological examinationBilateral paralysisProgressive signsRespiratory deathsGeneral diseasesOlder menImmunity mechanismsDysphagiaNeuronophagiaCuffingEncephalitisPontineMalignancyDysfunctionDysarthria