2013
Methamphetamine-induced increases in putamen gray matter associate with inhibitory control
Groman SM, Morales AM, Lee B, London ED, Jentsch JD. Methamphetamine-induced increases in putamen gray matter associate with inhibitory control. Psychopharmacology 2013, 229: 527-538. PMID: 23748383, PMCID: PMC3770792, DOI: 10.1007/s00213-013-3159-9.Peer-Reviewed Original ResearchMeSH KeywordsAmphetamine-Related DisordersAnimalsChlorocebus aethiopsCognitionDiscrimination, PsychologicalDose-Response Relationship, DrugInhibition, PsychologicalMagnetic Resonance ImagingMaleMethamphetaminePositron-Emission TomographyPutamenReceptors, Dopamine D2Retention, PsychologyReversal LearningTime FactorsConceptsD2-like receptorsGray matterDrug usePositron emission tomography scanDopamine D2-like receptorsDrug-experienced individualsHuman methamphetamine usersRegimen of methamphetamineEmission tomography scanGray matter abnormalitiesMethamphetamine-induced increasesDrug-induced changesInhibitory controlNeurobiological risk factorsDopaminergic markersRisk factorsTomography scanDAT availabilityRight putamenTransporter availabilityPharmacological effectsStructural abnormalitiesRegimenMagnetic resonance imagesObjectivesThe purpose
2012
An Evaluation of the Evidence that Methamphetamine Abuse Causes Cognitive Decline in Humans
Dean AC, Groman SM, Morales AM, London ED. An Evaluation of the Evidence that Methamphetamine Abuse Causes Cognitive Decline in Humans. Neuropsychopharmacology 2012, 38: 259-274. PMID: 22948978, PMCID: PMC3527116, DOI: 10.1038/npp.2012.179.Peer-Reviewed Original ResearchConceptsCognitive declineCognitive difficultiesMA abuseLine of researchCognitive functionCognitive deficitsModerator variablesMiddle adulthoodCross-sectional human studiesBrain structuresTwin studiesAbuseIllicit substancesMethamphetamine abuseAbstinenceCognitionMethamphetamineIndividualsCausal relationshipDifficultiesRelationshipHuman studiesDeficitsFindingsAdulthood