2019
Bi‐directional modulation of food habit expression by the endocannabinoid system
Gianessi CA, Groman SM, Taylor JR. Bi‐directional modulation of food habit expression by the endocannabinoid system. European Journal Of Neuroscience 2019, 49: 1610-1622. PMID: 30589475, PMCID: PMC7790508, DOI: 10.1111/ejn.14330.Peer-Reviewed Original ResearchConceptsCannabinoid receptor type 1Endocannabinoid systemTransient receptor potential cationHabitual respondingExpression of habitsMale C57BL/6 miceEndocannabinoid transport inhibitor AM404Potential pharmacological strategiesSubstance use disordersReceptor type 1Bi-directional modulationC57BL/6 micePharmacological strategiesCB1 receptorsPharmacological stimulationUse disordersEnzyme inhibitorsMental disordersType 1Neural circuitsNeuromodulatory systemsGoal-directed actionsSimilar reductionAM404Habit learning
2018
Neurochemical and Behavioral Dissections of Decision-Making in a Rodent Multistage Task
Groman SM, Massi B, Mathias SR, Curry DW, Lee D, Taylor JR. Neurochemical and Behavioral Dissections of Decision-Making in a Rodent Multistage Task. Journal Of Neuroscience 2018, 39: 295-306. PMID: 30413646, PMCID: PMC6325257, DOI: 10.1523/jneurosci.2219-18.2018.Peer-Reviewed Original ResearchConceptsMultistage taskBehavioral platformDopamine toneDecision Making TaskValue-based choiceDecision-making taskNovel behavioral paradigmModel-based learningConsequences of actionsReinforcement learning systemNeuroscience studiesBehavioral paradigmsBiobehavioral mechanismsVentral striatumNeurobehavioral levelBehavioral dissectionNovel analytic approachCortex correlatesRetrospective appraisalChoice behaviorTaskBehavioral mechanismsMental disordersModel-based systemLearning