Emerging Role of PACAP as a New Potential Therapeutic Target in Major Diabetes Complications
Marzagalli R, Scuderi S, Drago F, Waschek J, Castorina A. Emerging Role of PACAP as a New Potential Therapeutic Target in Major Diabetes Complications. International Journal Of Endocrinology 2015, 2015: 160928. PMID: 26074958, PMCID: PMC4446501, DOI: 10.1155/2015/160928.Peer-Reviewed Original ResearchMajor complicationsNeuropeptide pituitary adenylate cyclaseMajor diabetes complicationsMajor diabetic complicationsNew potential therapeutic targetsCause of morbidityCause of diabetesPituitary adenylate cyclasePotential therapeutic targetRole of PACAPPancreatic islet dysfunctionLongstanding diabetesDiabetes complicationsRange of pathologiesDiabetic complicationsHyperglycemic stateMillions of individualsIslet dysfunctionPeptide-based therapiesComplicationsTherapeutic targetDiabetesAdenylate cyclaseSecondary damageLife expectancy