2024
Early goal enteral nutrition associated with decreased in-hospital death in mechanically ventilated critically ill adults: a retrospective cohort study
Powierza C, Doyle M, Wasden K, Intihar T, Korwin A, Honiden S, Knauert M. Early goal enteral nutrition associated with decreased in-hospital death in mechanically ventilated critically ill adults: a retrospective cohort study. BMJ Open Respiratory Research 2024, 11: e001962. PMID: 38749534, PMCID: PMC11097881, DOI: 10.1136/bmjresp-2023-001962.Peer-Reviewed Original ResearchConceptsEarly enteral nutritionIn-hospital deathCritically ill adultsRetrospective cohort studyDays of intubationEnteral nutritionIll adultsAdult patientsCohort studyAssociated with decreased in-hospital deathsMechanically ventilated critically ill adultsGoal enteral nutritionIncreased hospital dischargeInitiation of ENCritically ill adult patientsMechanically ventilated adult patientsIncidence of in-hospital deathMedical intensive care unitAssociated with significant improvementsIll adult patientsDose of ENIntensive care unitClinical outcomesImprove mortalityPrimary outcome
2022
Bedside monitoring of hypoxic ischemic brain injury using low-field, portable brain magnetic resonance imaging after cardiac arrest
Beekman R, Crawford A, Mazurek MH, Prabhat AM, Chavva IR, Parasuram N, Kim N, Kim JA, Petersen N, de Havenon A, Khosla A, Honiden S, Miller PE, Wira C, Daley J, Payabvash S, Greer DM, Gilmore EJ, Kimberly W, Sheth KN. Bedside monitoring of hypoxic ischemic brain injury using low-field, portable brain magnetic resonance imaging after cardiac arrest. Resuscitation 2022, 176: 150-158. PMID: 35562094, PMCID: PMC9746653, DOI: 10.1016/j.resuscitation.2022.05.002.Peer-Reviewed Original ResearchConceptsCardiac arrestBrain injuryHypoxic-ischemic brain injuryAdverse neurological outcomesIschemic brain injurySingle-center studyBrain magnetic resonanceBrain injury severityBoard-certified neuroradiologistsLow-field MRIFLAIR signal intensityNeurological outcomeCA patientsIll patientsMRI findingsCA survivorsCenter studyMRI examinationsClinical careHigh riskInjury severityPatientsSignal intensityBedside monitoringMR imaging
2019
Reconsidering Nutritional Support in Critically Ill Patients
Korwin A, Honiden S. Reconsidering Nutritional Support in Critically Ill Patients. Seminars In Respiratory And Critical Care Medicine 2019, 40: 580-593. PMID: 31826259, DOI: 10.1055/s-0039-1697967.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCircadian RhythmCritical CareCritical IllnessEnteral NutritionHumansIntensive Care UnitsNutritional StatusNutritional SupportConceptsIntensive care unitIll patientsGood nutrition practicesNeeds of patientsProvision of nutritionICU nutritionSupportive careActive therapyNutritional supportCare unitFeeding interruptionsCritical careNutrition practicesGastrointestinal physiologyPatientsCircadian rhythmFeeding pumpProcess of recoveryCareMore researchNutritionProtein synthesisNon-continuous modeTherapyClinicians
2008
Early versus late intravenous insulin administration in critically ill patients
Honiden S, Schultz A, Im SA, Nierman DM, Gong MN. Early versus late intravenous insulin administration in critically ill patients. Intensive Care Medicine 2008, 34: 881. PMID: 18180902, PMCID: PMC2486366, DOI: 10.1007/s00134-007-0978-3.Peer-Reviewed Original ResearchConceptsIntensive insulin therapyHospital mortalityICU admissionEarly therapyEarly intensive insulin therapyMore ventilator-free daysDecreased hospital mortalityLower ICU mortalityShorter ICU stayVentilator-free daysLower hospital mortalityProspective cohort studyShorter hospital stayTertiary teaching hospitalIntravenous insulin administrationPatientsThe studyAdmission diagnosisHospital stayICU mortalityICU stayCohort studyInsulin therapyMedical ICUDirection of associationIll patients