2021
Coupling lipid synthesis with nuclear envelope remodeling
Barger SR, Penfield L, Bahmanyar S. Coupling lipid synthesis with nuclear envelope remodeling. Trends In Biochemical Sciences 2021, 47: 52-65. PMID: 34556392, PMCID: PMC9943564, DOI: 10.1016/j.tibs.2021.08.009.Peer-Reviewed Original ResearchConceptsNuclear envelopeEndoplasmic reticulumNuclear membraneNuclear envelope remodelingLipid-protein interactionsBiosynthesis of lipidsNE remodelingGenome protectionDynamic remodeling processesNE dynamicsLipid speciesCell growthBilayer lipidsLipid synthesisNew roleMembraneLipidsRecent evidenceRemodeling processGenomeRemodelingBiosynthesisProtective barrierSpeciesProtein
2020
Regulated lipid synthesis and LEM2/CHMP7 jointly control nuclear envelope closure
Penfield L, Shankar R, Szentgyörgyi E, Laffitte A, Mauro MS, Audhya A, Müller-Reichert T, Bahmanyar S. Regulated lipid synthesis and LEM2/CHMP7 jointly control nuclear envelope closure. Journal Of Cell Biology 2020, 219: e201908179. PMID: 32271860, PMCID: PMC7199858, DOI: 10.1083/jcb.201908179.Peer-Reviewed Original ResearchConceptsER membraneNuclear permeability barrierESCRT-III componentsC. elegans oocytesMeiotic spindle microtubulesDe novo glycerolipid synthesisPermeability barrierGlycerolipid synthesisESCRT componentsESCRT-IIIProtein phosphataseCytoplasmic membraneSpindle microtubulesNE permeabilityMeiotic spindleLipid synthesis
2018
The Inner Nuclear Membrane Takes On Lipid Metabolism
Merta H, Bahmanyar S. The Inner Nuclear Membrane Takes On Lipid Metabolism. Developmental Cell 2018, 47: 397-399. PMID: 30458132, DOI: 10.1016/j.devcel.2018.11.005.Peer-Reviewed Original Research