2008
Preoperative β-blocker use: impact of national guidelines on clinical practice
Akhtar S, Assaad, Amin M, Holt NF, Barash PG, Silverman DG. Preoperative β-blocker use: impact of national guidelines on clinical practice. Journal Of Clinical Anesthesia 2008, 20: 122-128. PMID: 18410867, DOI: 10.1016/j.jclinane.2007.09.012.Peer-Reviewed Original ResearchConceptsBeta-blocker groupPost-guideline patientsPre-guideline groupVascular surgery patientsCoronary artery bypassTarget HRArtery bypassSurgery patientsPerioperative beta-blocker therapyPreoperative beta-blocker useTertiary care teaching hospitalMean HRElective vascular surgeryPost-guideline groupVascular surgery groupBeta-blocker therapyBeta-blocker useUnpaired t-testEligible patientsSurgery groupPreanesthetic evaluationVascular surgeryPresurgical patientsTeaching hospitalObservational study
2005
Preoperative β-blocker use: is titration to a heart rate of 60 beats per minute a consistently attainable goal?
Akhtar S, Amin M, Tantawy H, Senior A, Barash PG, Silverman DG. Preoperative β-blocker use: is titration to a heart rate of 60 beats per minute a consistently attainable goal? Journal Of Clinical Anesthesia 2005, 17: 191-197. PMID: 15896586, DOI: 10.1016/j.jclinane.2004.06.020.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic beta-AntagonistsAgedCoronary Artery BypassFemaleHeart RateHumansMaleMiddle AgedPreoperative CareRetrospective StudiesVascular Surgical ProceduresConceptsPreinduction heart ratePerioperative beta-blocker useBeta-blocker useHeart rateCABG patientsEligible patientsSurgery patientsCoronary artery bypass graft surgeryArtery bypass graft surgeryTertiary care teaching hospitalBeta-blocker intoleranceCABG surgery patientsBeta-blocker therapyBypass graft surgeryVascular surgery patientsRetrospective observational studyUnpaired t-testBlocker groupGraft surgeryNoncardiac surgeryVascular patientsVascular surgeryTeaching hospitalObservational studyCurrent recommendations
2004
Assessment and management of patients with ischemic heart disease
Akhtar S, Silverman DG. Assessment and management of patients with ischemic heart disease. Critical Care Medicine 2004, 32: s126-s136. PMID: 15064671, DOI: 10.1097/01.ccm.0000121576.73871.2d.Peer-Reviewed Original ResearchConceptsIschemic heart diseasePerioperative cardiac morbidityHeart diseaseCardiac morbidityNoncardiac surgeryPerioperative cardiovascular outcomesPreoperative evaluation processPerioperative myocardial infarctionManagement of patientsAlpha-2 agonistsCardiac-specific biomarkersAmerican Heart AssociationIntraoperative anesthetic techniqueReview of literatureCardiovascular outcomesPerioperative managementPharmacologic therapyPostoperative managementAnesthetic techniqueHeart AssociationHemodynamic controlJoint guidelinesMyocardial infarctionAmerican CollegeHemodynamic stress
2002
Perioperative Use of Beta-Blockers: Past, Present, and Future
Akhtar S, Barash PG. Perioperative Use of Beta-Blockers: Past, Present, and Future. International Anesthesiology Clinics 2002, 40: 133-157. PMID: 11897941, DOI: 10.1097/00004311-200204000-00012.Peer-Reviewed Original ResearchAdrenergic beta-AntagonistsHemodynamicsHumansMyocardial InfarctionPreoperative CareReceptors, Adrenergic, beta
1999
The effect of heart rate control on myocardial ischemia among high-risk patients after vascular surgery.
Raby K, Brull S, Timimi F, Akhtar S, Rosenbaum S, Naimi C, Whittemore A. The effect of heart rate control on myocardial ischemia among high-risk patients after vascular surgery. Anesthesia & Analgesia 1999, 88: 477-82. PMID: 10071990, DOI: 10.1097/00000539-199903000-00002.Peer-Reviewed Original ResearchConceptsHeart rate controlMean heart ratePostoperative cardiac eventsHigh-risk patientsST-segment depressionIschemic thresholdPostoperative ischemiaMyocardial ischemiaVascular surgeryHeart rateCardiac eventsEsmolol patientsPlacebo patientsPreoperative ischemiaCardiac complicationsHigh riskHigh-risk vascular surgery patientsBeta-adrenergic blocker therapyMajor postoperative cardiac eventsStrict heart rate controlElective vascular surgeryIncidence of ischemiaPostoperative heart ratePostoperative myocardial ischemiaPreoperative myocardial ischemiaThe Effect of Heart Rate Control on Myocardial Ischemia Among High-Risk Patients After Vascular Surgery
Raby K, Brull S, Timimi F, Akhtar S, Rosenbaum S, Naimi C, Whittemore A. The Effect of Heart Rate Control on Myocardial Ischemia Among High-Risk Patients After Vascular Surgery. Anesthesia & Analgesia 1999, 88: 477-482.. DOI: 10.1213/00000539-199903000-00002.Peer-Reviewed Original ResearchConceptsHeart rate controlMean heart ratePostoperative cardiac eventsHigh-risk patientsST-segment depressionIschemic thresholdPostoperative ischemiaMyocardial ischemiaVascular surgeryHeart rateCardiac eventsEsmolol patientsPlacebo patientsPreoperative ischemiaCardiac complicationsHigh riskHigh-risk vascular surgery patientsBeta-adrenergic blocker therapyMajor postoperative cardiac eventsStrict heart rate controlElective vascular surgeryIncidence of ischemiaPostoperative heart ratePostoperative myocardial ischemiaPreoperative myocardial ischemia