2005
beamter/deltaC and the role of Notch ligands in the zebrafish somite segmentation, hindbrain neurogenesis and hypochord differentiation
Jülich D, Lim C, Round J, Nicolaije C, Schroeder J, Davies A, Geisler R, Lewis J, Jiang Y, Holley S, Consortium T. beamter/deltaC and the role of Notch ligands in the zebrafish somite segmentation, hindbrain neurogenesis and hypochord differentiation. Developmental Biology 2005, 286: 391-404. PMID: 16125692, DOI: 10.1016/j.ydbio.2005.06.040.Peer-Reviewed Original ResearchConceptsPresomitic mesodermSomite segmentationZebrafish genetic screenEGF repeatsGenetic screenOscillating expressionOscillating genesSegmentation clockDouble mutantDSL domainSubcellular localizationAntimorphic effectsStrong defectsGene expressionNotch pathwayNotch ligandsNew allelesIndividual cellsDeltaCTriple fluorescentCoordinated oscillationsGenesAllelesExpressionLigand functionsIntegrinα5 and Delta/Notch Signaling Have Complementary Spatiotemporal Requirements during Zebrafish Somitogenesis
Ju¨lich D, Geisler R, Consortium T, Holley S. Integrinα5 and Delta/Notch Signaling Have Complementary Spatiotemporal Requirements during Zebrafish Somitogenesis. Developmental Cell 2005, 8: 575-586. PMID: 15809039, DOI: 10.1016/j.devcel.2005.01.016.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsAnimals, Genetically ModifiedBody PatterningCell PolarityExtracellular MatrixFibronectinsGene Expression Regulation, DevelopmentalIn Situ HybridizationIntegrin alpha5Intracellular Signaling Peptides and ProteinsMembrane ProteinsMolecular Sequence DataMorphogenesisPhenotypePoint MutationReceptors, NotchRecombinant Fusion ProteinsSignal TransductionSomitesZebrafishZebrafish ProteinsConceptsFibronectin matrix assemblyDelta/Notch signalingMatrix assemblyNotch pathway mutantsEntire body axisZebrafish somitogenesisVertebrate embryogenesisPathway mutantsDouble mutantSomite defectsSomite formationPosterior somitesGenetic controlSomitogenesisNotch signalingNotch pathwayEpithelial transitionSpatiotemporal requirementsBody axisCell polarizationSegmentation defectsPoint mutationsMutantsComplete lossSkeletal muscle
2000
Control of her1 expression during zebrafish somitogenesis by a Delta-dependent oscillator and an independent wave-front activity
Holley S, Geisler R, Nüsslein-Volhard C. Control of her1 expression during zebrafish somitogenesis by a Delta-dependent oscillator and an independent wave-front activity. Genes & Development 2000, 14: 1678-1690. PMID: 10887161, PMCID: PMC316735, DOI: 10.1101/gad.14.13.1678.Peer-Reviewed Original ResearchConceptsAnterior presomitic mesodermPresomitic mesodermGene expressionNotch pathwayHER1 expressionZebrafish genesZebrafish somitogenesisEmbryos mutantSomite morphogenesisMolecular clockExpression patternsExpression de novoExpression oscillatesNotch ligandsPathway upstreamSomitogenesisBorder formationConsecutive somitesDe novoSomitesExpressionWave-front modelPathwayClockHER1