2021
Imaging Features at the Periphery: Hemodynamics, Pathophysiology, and Effect on LI-RADS Categorization.
Consul N, Sirlin CB, Chernyak V, Fetzer DT, Masch WR, Arora SS, Do RKG, Marks RM, Fowler KJ, Borhani AA, Elsayes KM. Imaging Features at the Periphery: Hemodynamics, Pathophysiology, and Effect on LI-RADS Categorization. RadioGraphics 2021, 41: 1657-1675. PMID: 34559586, DOI: 10.1148/rg.2021210019.Peer-Reviewed Original ResearchConceptsHepatocellular carcinomaEnhancement patternLiver observationsCapsule appearanceRim arterial phase hyperenhancementAncillary featuresNon-HCC malignanciesLocal-regional therapyArterial phase hyperenhancementLiver Imaging ReportingDynamic contrast-enhanced imagingDifferent enhancement patternsImaging-based diagnosisContrast-enhanced imagingPeripheral washoutArterioportal shuntTargetoid appearanceNodular enhancementCorona enhancementBenign entityTreatment responseLI-RADSRisk populationsLiver lesionsSpecific diagnosisHCC: role of pre- and post-treatment tumor biology in driving adverse outcomes and rare responses to therapy
Arora S, Catania R, Borhani A, Horvat N, Fowler K, Harmath C. HCC: role of pre- and post-treatment tumor biology in driving adverse outcomes and rare responses to therapy. Abdominal Radiology 2021, 46: 3686-3697. PMID: 34195886, DOI: 10.1007/s00261-021-03192-8.Peer-Reviewed Original ResearchConceptsHepatocellular carcinomaTumor biologyHCC tumor biologyRare responsesTreatment hepatocellular carcinomaPost-treatment responsePrognostic featuresAbscopal effectAdverse outcomesCancer deathIdeal therapyEffective therapyImaging featuresDisease evolveIndividual patientsLiver cancerMore therapiesTumor behaviorTreatment planParticular tumorTherapyClinical useTreatment planningPatientsTumorsLI-RADS treatment response lexicon: review, refresh and resolve with emerging data
Ram R, Kampalath R, Shenoy-Bhangle AS, Arora S, Kielar AZ, Mendiratta-Lala M. LI-RADS treatment response lexicon: review, refresh and resolve with emerging data. Abdominal Radiology 2021, 46: 3549-3557. PMID: 34106301, DOI: 10.1007/s00261-021-03149-x.Peer-Reviewed Original ResearchMeSH KeywordsCarcinoma, HepatocellularCross-Sectional StudiesHumansLiver NeoplasmsMagnetic Resonance ImagingTomography, X-Ray ComputedConceptsTreatment response algorithmHepatocellular carcinomaRegional treatmentData System treatment response algorithmLI-RADS treatment response algorithmLoco-regional therapyLoco-regional treatmentLiver Imaging ReportingTreatment response assessmentCross-sectional modalitiesType of treatmentRegional therapyCurrent guidelinesTreatment responseResponse assessmentImaging ReportingCarcinomaTreatmentHepatocellular carcinoma: metastatic pathways and extra-hepatic findings
Arora S, Harmath C, Catania R, Mandler A, Fowler KJ, Borhani AA. Hepatocellular carcinoma: metastatic pathways and extra-hepatic findings. Abdominal Radiology 2021, 46: 3698-3707. PMID: 34091729, DOI: 10.1007/s00261-021-03151-3.Peer-Reviewed Original ResearchConceptsHepatocellular carcinomaExtrahepatic diseaseMetastatic diseaseManagement of patientsEarly metastatic diseaseCourse of treatmentExtrahepatic spreadDefinitive treatmentInitial presentationTreatment optionsPrecise stagingMetastatic pathwaysTumor biologySystemic spreadMolecular derangementsPatientsDiseasePotential roleDifferent pathwaysMolecular characteristicsTreatmentPathwayCarcinomaDerangementStagingRole of the radiologist at HCC multidisciplinary conference and use of the LR-TR algorithm for improving workflow
Shenoy-Bhangle AS, Tsai LL, Masciocchi M, Arora SS, Kielar AZ. Role of the radiologist at HCC multidisciplinary conference and use of the LR-TR algorithm for improving workflow. Abdominal Radiology 2021, 46: 3558-3564. PMID: 33904990, DOI: 10.1007/s00261-021-03094-9.Peer-Reviewed Original ResearchConceptsLiver-directed locoregional therapiesLR-TR algorithmHepatocellular carcinomaLocoregional therapyMultidisciplinary conferenceLiver observationsTreatment of HCCLiver-directed therapiesLiver Imaging ReportingOptimal patient managementPost-treatment imagingRadiologic findingsLiver diseaseOncology patientsTransplant eligibilityInterdisciplinary managementHCC screeningPatient managementMultidisciplinary discussionPatient careImaging ReportingPatientsTherapyRadiologistsDisease
2019
An update for LI‐RADS: Version 2018. Why so soon after version 2017?
Kielar AZ, Chernyak V, Bashir MR, K. R, Fowler KJ, Santillan C, Sirlin CB, Mitchell DG, Cerny M, Tang A, Elsayes KM, Kamaya A, Kono Y, Arora SS. An update for LI‐RADS: Version 2018. Why so soon after version 2017? Journal Of Magnetic Resonance Imaging 2019, 50: 1990-1991. PMID: 30864185, DOI: 10.1002/jmri.26715.Peer-Reviewed Original Research
2018
White paper of the Society of Abdominal Radiology hepatocellular carcinoma diagnosis disease-focused panel on LI-RADS v2018 for CT and MRI
Elsayes KM, Kielar AZ, Elmohr MM, Chernyak V, Masch WR, Furlan A, Marks RM, Cruite I, Fowler KJ, Tang A, Bashir MR, Hecht EM, Kamaya A, Jambhekar K, Kamath A, Arora S, Bijan B, Ash R, Kassam Z, Chaudhry H, McGahan JP, Yacoub JH, McInnes M, Fung AW, Shanbhogue K, Lee J, Deshmukh S, Horvat N, Mitchell DG, Do RKG, Surabhi VR, Szklaruk J, Sirlin CB. White paper of the Society of Abdominal Radiology hepatocellular carcinoma diagnosis disease-focused panel on LI-RADS v2018 for CT and MRI. Abdominal Radiology 2018, 43: 2625-2642. PMID: 30155697, DOI: 10.1007/s00261-018-1744-4.Peer-Reviewed Original ResearchConceptsLI-RADS v2018Hepatocellular carcinomaClinical practice guidanceDiagnostic imaging criteriaImaging-based diagnosisReporting Data SystemSurveillance ultrasoundLiver diseaseImaging criteriaArterial phaseLI-RADSClinical careOrgan procurementLiver imagingDiagnostic algorithmV2018American AssociationPractice guidanceThreshold growthNetwork definitionAASLDPatientsCarcinomaData System