2021
HCC: role of pre- and post-treatment tumor biology in driving adverse outcomes and rare responses to therapy
Arora S, Catania R, Borhani A, Horvat N, Fowler K, Harmath C. HCC: role of pre- and post-treatment tumor biology in driving adverse outcomes and rare responses to therapy. Abdominal Radiology 2021, 46: 3686-3697. PMID: 34195886, DOI: 10.1007/s00261-021-03192-8.Peer-Reviewed Original ResearchConceptsHepatocellular carcinomaTumor biologyHCC tumor biologyRare responsesTreatment hepatocellular carcinomaPost-treatment responsePrognostic featuresAbscopal effectAdverse outcomesCancer deathIdeal therapyEffective therapyImaging featuresDisease evolveIndividual patientsLiver cancerMore therapiesTumor behaviorTreatment planParticular tumorTherapyClinical useTreatment planningPatientsTumorsRole of the radiologist at HCC multidisciplinary conference and use of the LR-TR algorithm for improving workflow
Shenoy-Bhangle AS, Tsai LL, Masciocchi M, Arora SS, Kielar AZ. Role of the radiologist at HCC multidisciplinary conference and use of the LR-TR algorithm for improving workflow. Abdominal Radiology 2021, 46: 3558-3564. PMID: 33904990, DOI: 10.1007/s00261-021-03094-9.Peer-Reviewed Original ResearchConceptsLiver-directed locoregional therapiesLR-TR algorithmHepatocellular carcinomaLocoregional therapyMultidisciplinary conferenceLiver observationsTreatment of HCCLiver-directed therapiesLiver Imaging ReportingOptimal patient managementPost-treatment imagingRadiologic findingsLiver diseaseOncology patientsTransplant eligibilityInterdisciplinary managementHCC screeningPatient managementMultidisciplinary discussionPatient careImaging ReportingPatientsTherapyRadiologistsDiseaseMR-Guided High-Intensity Directional Ultrasound Ablation of Prostate Cancer
Galgano SJ, Planz VB, Arora S, Rais-Bahrami S. MR-Guided High-Intensity Directional Ultrasound Ablation of Prostate Cancer. Current Urology Reports 2021, 22: 3. PMID: 33403460, DOI: 10.1007/s11934-020-01020-y.Peer-Reviewed Original ResearchConceptsTreatment modalitiesProstate cancerFocal therapyFavorable side effect profileLong-term oncologic outcomesSide effect profileMR-Guided HighNovel treatment modalitiesPromising early resultsProstate cancer diagnosisOncologic outcomesDefinitive treatmentUrinary sphincterNeurovascular bundleRadical prostatectomyActive surveillanceRadiation therapyFocal ablationHeterogeneous diseaseProstate glandReviewThe goalTherapyUltrasound ablationCancer diagnosisProstate MRI
2017
Therapeutic Ultrasound and Prostate Cancer
Sundaram KM, Chang SS, Penson DF, Arora S. Therapeutic Ultrasound and Prostate Cancer. Seminars In Interventional Radiology 2017, 34: 187-200. PMID: 28579687, PMCID: PMC5453783, DOI: 10.1055/s-0037-1602710.Peer-Reviewed Original ResearchProstate cancerIntermediate-risk prostate cancerRisk prostate cancerAdverse event ratesInvasive alternative treatmentExternal beam radiotherapyDefinitive therapyAdverse eventsUrinary incontinenceClinical efficacyErectile dysfunctionRadical prostatectomyClinical trialsFocal therapyAlternative treatmentFDA approvalEvent ratesUltrasound ablationMRI guidanceTherapeutic ultrasoundUltrasound approachTherapyHIFU deviceCancerUltrasound