2023
Tau epicenter identification and connectivity in clinically heterogeneous Alzheimer’s disease variants
Trainer A, Xu W, Chase A, O'Dell R, Tun S, Li J, Ju S, van Dyck C, Mecca A, Fredricks C. Tau epicenter identification and connectivity in clinically heterogeneous Alzheimer’s disease variants. Alzheimer's & Dementia 2023, 19 DOI: 10.1002/alz.079435.Peer-Reviewed Original ResearchAmnestic Alzheimer's diseaseLogopenic variant primary progressive aphasiaPosterior cortical atrophyFunctional connectivity mapsHigher tau burdenFunctional connectivityTau burdenAlzheimer's diseaseConnectivity mapsLongitudinal tau-PETSpread of tauVariant primary progressive aphasiaFusiform gyrusFrontal eye fieldPrimary progressive aphasiaBrains of participantsTau PET scansSuperior parietal lobulePatient-specific biomarkersCortical atrophyCommon subtypeTau-PETHealthy controlsParietooccipital cortexPET scans
2007
Rapid Changes in Throughput from Single Motor Cortex Neurons to Muscle Activity
Davidson AG, Chan V, O'Dell R, Schieber MH. Rapid Changes in Throughput from Single Motor Cortex Neurons to Muscle Activity. Science 2007, 318: 1934-1937. PMID: 18096808, DOI: 10.1126/science.1149774.Peer-Reviewed Original ResearchConceptsSingle motor cortex neuronsMotor cortex neuronsMotor cortex outputCortex neuronsMuscle activityFunctional connectivityOngoing muscle activityAlpha-motoneuron poolModulation of excitabilityNeuron firing rateFiring rateNeuronsNeuronal synchronizationBehavioral epochsCortexSuch reorganizationExcitabilityActivity