2022
Depression and Anxiety in Patients With Lichen Sclerosus
Fan R, Leasure AC, Maisha FI, Little AJ, Cohen JM. Depression and Anxiety in Patients With Lichen Sclerosus. JAMA Dermatology 2022, 158: 953-954. PMID: 35704313, PMCID: PMC9201736, DOI: 10.1001/jamadermatol.2022.1964.Peer-Reviewed Original ResearchVaccination Recommendations for Psoriasis and Atopic Dermatitis Patients on Biologic Therapy: A Practical Guide.
Fan R, Cohen JM. Vaccination Recommendations for Psoriasis and Atopic Dermatitis Patients on Biologic Therapy: A Practical Guide. The Yale Journal Of Biology And Medicine 2022, 95: 249-255. PMID: 35782480, PMCID: PMC9235258.Peer-Reviewed Original ResearchConceptsAtopic dermatitis patientsBiologic therapyVaccination recommendationsDermatitis patientsTreatment of psoriasisNovel biologic therapiesIL-17IL-23Atopic dermatitisIL-12/23Vaccine administrationClinical dataHealthcare providersAvailable guidelinesPsoriasisTherapyUnique considerationsPatientsPractical guideVaccinationDermatitisTNFαInfectionDermatologistsAdministration
2021
Association between atopic dermatitis and COVID-19 infection: A case-control study in the All of Us research program
Fan R, Leasure AC, Damsky W, Cohen JM. Association between atopic dermatitis and COVID-19 infection: A case-control study in the All of Us research program. JAAD International 2021, 6: 77-81. PMID: 34977817, PMCID: PMC8712258, DOI: 10.1016/j.jdin.2021.12.007.Peer-Reviewed Original ResearchCOVID-19 infectionCase-control studyMultivariable analysisAD patientsAtopic dermatitis patientsCOVID-19 outcomesCOVID-19COVID-19 diagnosisElectronic health recordsCommon comorbiditiesAtopic dermatitisDermatitis patientsAD severityCOVID-19 casesUS cohortRisk factorsClinical dataAD casesUs Research ProgramComorbiditiesDiverse cohortPatientsInfectionCohortHealth records
2017
Feasibility of monitoring advanced melanoma patients using cell‐free DNA from plasma
Gangadhar T, Savitch S, Yee S, Xu W, Huang A, Harmon S, Lieberman D, Soucier D, Fan R, Black T, Morrissette J, Salathia N, Waters J, Zhang S, Toung J, van Hummelen P, Fan J, Xu X, Amaravadi R, Schuchter L, Karakousis G, Hwang W, Carpenter E. Feasibility of monitoring advanced melanoma patients using cell‐free DNA from plasma. Pigment Cell & Melanoma Research 2017, 31: 73-81. PMID: 28786531, PMCID: PMC5742050, DOI: 10.1111/pcmr.12623.Peer-Reviewed Original ResearchConceptsCell-free DNAStage III/IV patientsTissue next-generation sequencingAdvanced melanoma patientsMonitoring of patientsPrevious therapyIV patientsAdvanced melanomaMelanoma patientsTumor burdenBlood drawUltra-deep sequencingPatientsPlasma mutationsLiquid biopsyNext-generation sequencingFrequent mutationsAllele fractionTherapyMore mutationsMutationsBiopsyMelanomaBRAF
2016
Detection of Therapeutically Targetable Driver and Resistance Mutations in Lung Cancer Patients by Next-Generation Sequencing of Cell-Free Circulating Tumor DNA
Thompson J, Yee S, Troxel A, Savitch S, Fan R, Balli D, Lieberman D, Morrissette J, Evans T, Bauml J, Aggarwal C, Kosteva J, Alley E, Ciunci C, Cohen R, Bagley S, Stonehouse-Lee S, Sherry V, Gilbert E, Langer C, Vachani A, Carpenter E. Detection of Therapeutically Targetable Driver and Resistance Mutations in Lung Cancer Patients by Next-Generation Sequencing of Cell-Free Circulating Tumor DNA. Clinical Cancer Research 2016, 22: 5772-5782. PMID: 27601595, PMCID: PMC5448134, DOI: 10.1158/1078-0432.ccr-16-1231.Peer-Reviewed Original ResearchConceptsNon-small cell lung cancerCtDNA next-generation sequencingResistance mutationsNext-generation sequencingTissue sequencingAdvanced non-small cell lung cancerActionable EGFR mutationsCell lung cancerProgressive diseaseConsecutive patientsCtDNA sequencingTargetable driversLung cancerClinical trialsDisease progressionEGFR mutationsUltra-deep sequencingPatient managementExperimental therapiesTumor genotypingCtDNA samplesTissue biopsiesPatientsAccurate diagnosisBlood collection