2024
Molecular and cellular neurocardiology in heart disease
Habecker B, Bers D, Birren S, Chang R, Herring N, Kay M, Li D, Mendelowitz D, Mongillo M, Montgomery J, Ripplinger C, Tampakakis E, Winbo A, Zaglia T, Zeltner N, Paterson D. Molecular and cellular neurocardiology in heart disease. The Journal Of Physiology 2024 PMID: 38778747, PMCID: PMC11582088, DOI: 10.1113/jp284739.Peer-Reviewed Original ResearchPatient-specific stem cellsHeart diseaseArea of controversyCardiac dysautonomiaNovel imaging techniquesSympathetic impairmentHeart failureTherapeutic opportunitiesNeurochemical pathwaysStem cellsCellular basisIntracellular pathwaysDiscovery of molecular pathwaysMolecular pathwaysDiseaseImaging techniquesHeartTarget discoverySpatial transcriptomicsPathwayStudy diseasesDysautonomiaPatients
2023
The vagus nerve in cardiovascular physiology and pathophysiology: From evolutionary insights to clinical medicine
Rajendran P, Hadaya J, Khalsa S, Yu C, Chang R, Shivkumar K. The vagus nerve in cardiovascular physiology and pathophysiology: From evolutionary insights to clinical medicine. Seminars In Cell And Developmental Biology 2023, 156: 190-200. PMID: 36641366, PMCID: PMC10336178, DOI: 10.1016/j.semcdb.2023.01.001.Peer-Reviewed Original ResearchConceptsParasympathetic nervous systemNervous systemEvolutionary insightsGenetic diversityComparative biologySympathetic nervous systemParasympathetic dysfunctionVagal neuronsBlood pressureVagal efferentsAfferent innervationVagus nerveHeart diseaseCardiovascular functionCardiovascular diseaseHeart rateTherapeutic potentialCardiovascular physiologyDiseaseClinical medicineHeartBiologyDiversityInnervationNerve