1995
Age-dependent Alterations in beta-adrenergic Responsiveness of Rat Detrusor Smooth Muscle
Nishimoto T, Latifpour J, Wheeler M, Yoshida M, Weiss R. Age-dependent Alterations in beta-adrenergic Responsiveness of Rat Detrusor Smooth Muscle. Journal Of Urology 1995, 153: 1701-1705. PMID: 7715014, DOI: 10.1016/s0022-5347(01)67508-6.Peer-Reviewed Original ResearchConceptsElectrical field stimulationMaximum relaxant responseBeta-adrenergic receptorsMuscle stripsRelaxant responsesRelaxant effectTonic contractionMaximal KCl-induced contractionRat detrusor smooth muscleAge groupsMale Fischer 344 ratsDetrusor muscle stripsEFS-induced contractionsKCl-induced contractionBeta-adrenergic responsivenessDetrusor smooth muscleFischer 344 ratsBeta-adrenergic stimulationAge-dependent alterationsAge-related decreaseCyclic AMP productionDibutyryl cyclic AMPRat detrusorPhasic contractionsBladder detrusor
1994
Involvement of nitric oxide and cyclic GMP in rabbit urethral relaxation
Dokita S, Smith S, Nishimoto T, Wheeler M, Weiss R. Involvement of nitric oxide and cyclic GMP in rabbit urethral relaxation. European Journal Of Pharmacology 1994, 266: 269-275. PMID: 7513645, DOI: 10.1016/0922-4106(94)90136-8.Peer-Reviewed Original ResearchConceptsNitric oxide synthase activityTransmural nerve stimulationOxide synthase activityRabbit urethraNerve stimulationNOS activityL-arginineSoluble nitric oxide synthaseNitric oxide synthase inhibitorRelaxation responseNitric oxideCyclic GMPOxide synthase inhibitorNitric oxide synthaseCyclic GMP levelsUrethral relaxationNG-nitroRank orderOxide synthaseSynthase activityNG-methylSynthase inhibitorElectrical stimulationUrethraSame rank order
1991
NG-nitro-L-arginine inhibits non-adrenergic, non-cholinergic relaxation in rabbit urethral smooth muscle
Dokita S, Morgan W, Wheeler M, Yoshida M, Latifpour J, Weiss R. NG-nitro-L-arginine inhibits non-adrenergic, non-cholinergic relaxation in rabbit urethral smooth muscle. Life Sciences 1991, 48: 2429-2436. PMID: 1675415, DOI: 10.1016/0024-3205(91)90377-n.Peer-Reviewed Original ResearchConceptsElectrical field stimulationRelaxation responseNG-nitroField stimulationL-arginineSelective cyclic GMP phosphodiesterase inhibitorNitric oxideNon-cholinergic relaxationRabbit urethral smooth muscleNon-cholinergic nervesUrethral smooth muscleUrethral smooth muscle stripsSmooth muscle stripsL-arginine inhibitsSoluble guanylate cyclaseNitric oxide biosynthesisCyclic GMP phosphodiesterase inhibitorMuscle stripsSmooth musclePhosphodiesterase inhibitorGuanylate cyclaseCyclic GMPStimulationInhibitorsResponse
1985
"On" and "off" responses of guinea pig ureter
Hong K, Biancani P, Weiss R. "On" and "off" responses of guinea pig ureter. American Journal Of Physiology 1985, 248: c165-c169. PMID: 3917613, DOI: 10.1152/ajpcell.1985.248.1.c165.Peer-Reviewed Original Research
1982
Effect of obstruction on ureteral circumferential force-length relations
Biancani P, Hausman M, Weiss R. Effect of obstruction on ureteral circumferential force-length relations. American Journal Of Physiology 1982, 243: f204-f210. PMID: 7114220, DOI: 10.1152/ajprenal.1982.243.2.f204.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsElectric StimulationIn Vitro TechniquesMathematicsMuscle, SmoothPressureRabbitsTime FactorsUreteral ObstructionUrinationConceptsMuscle hypertrophyIntraluminal pressureCross-sectional muscle areaControl uretersPeak active forceUreteral diameterUreteral segmentActive circumferential stressObstructionUreterObstructed uretersContractile forceHypertrophyContractilityMuscle areaContractility resultsEffects of obstructionForce-length relationLaplace relationshipWkCorresponding doubling