2013
Monoarthritis risk stratification in Lyme disease
Schoen R. Monoarthritis risk stratification in Lyme disease. Nature Reviews Rheumatology 2013, 9: 261-262. PMID: 23567460, DOI: 10.1038/nrrheum.2013.47.Peer-Reviewed Original Research
1991
Treatment of refractory chronic Lyme arthritis with arthroscopic synovectomy
Schoen R, Aversa J, Rahn D, Steere A. Treatment of refractory chronic Lyme arthritis with arthroscopic synovectomy. Arthritis & Rheumatism 1991, 34: 1056-1060. PMID: 1859481, DOI: 10.1002/art.1780340817.Peer-Reviewed Original ResearchConceptsChronic Lyme arthritisLyme arthritisArthroscopic synovectomyMild functional limitationsLong-term followupRecurrent synovitisJoint inflammationAntibiotic therapyFollowup periodFunctional limitationsPatientsArthritisFirst monthSynovectomyFollowupSynovitisInflammationSurgeryTherapyKneeDiseaseMonths
1987
The clinical evolution of Lyme arthritis.
Steere A, Schoen R, Taylor E. The clinical evolution of Lyme arthritis. Annals Of Internal Medicine 1987, 107: 725-31. PMID: 3662285, DOI: 10.7326/0003-4819-107-5-725.Peer-Reviewed Original ResearchConceptsLyme arthritisClinical evolutionDisease onsetIntermittent attacksSubjective joint painErythema chronicum migransFrank arthritisChronic synovitisErosive diseaseJoint painAntibiotic therapyMusculoskeletal painJoint disabilityMean durationJoint abnormalitiesLarge jointsArthritisPatientsLyme diseaseSubsequent manifestationBrief episodesPainDiseaseEpisodesOnsetTreatment of Lyme disease
Steere A, Green J, Hutchinson G, Rahn D, Pachner A, Schoen R, Sigal L, Taylor E, Malawista S. Treatment of Lyme disease. International Journal Of Medical Microbiology 1987, 263: 352-356. PMID: 3109144, DOI: 10.1016/s0176-6724(87)80092-5.Peer-Reviewed Original ResearchMeSH KeywordsAdultArthritis, InfectiousChildErythromycinHumansLyme DiseaseNervous System DiseasesPenicillin VRandom AllocationTetracyclineConceptsPenicillin-treated patientsLyme diseaseHigh-dose intravenous penicillinAttacks of arthritisIntravenous penicillin GHalf of patientsMajor late complicationsEarly Lyme diseaseIntramuscular benzathine penicillinIntravenous penicillinLate complicationsAntibiotic therapyArthritis patientsBenzathine penicillinMotor deficitsNeurologic abnormalitiesLate diseaseLate symptomsPatientsPhenoxymethyl penicillinAntibiotic agentsComplete recoveryDiseasePenicillin GArthritis
1985
Successful Parenteral Penicillin Therapy of Established Lyme Arthritis
Steere A, Green J, Schoen R, Taylor E, Hutchinson G, Rahn D, Malawista S. Successful Parenteral Penicillin Therapy of Established Lyme Arthritis. New England Journal Of Medicine 1985, 312: 869-874. PMID: 3883177, DOI: 10.1056/nejm198504043121401.Peer-Reviewed Original ResearchMeSH KeywordsAdultArthritis, InfectiousClinical Trials as TopicDouble-Blind MethodFemaleHumansInjections, IntravenousLyme DiseaseMalePenicillin GConceptsLyme arthritisComplete resolutionDouble-blind placebo-controlled trialAttacks of arthritisIntravenous penicillin GParenteral penicillin therapyPlacebo-controlled trialPenicillin-treated patientsErythema chronicum migransMean followPenicillin therapyParenteral therapyParenteral penicillinIntraarticular corticosteroidsJoint fluidArthritisPatientsLyme spirocheteFurther experienceTherapyPenicillin GOptimal courseDaysCorticosteroidsPlacebo