2004
Idiopathic pulmonary fibrosis: new insights into pathogenesis
Noble PW, Homer RJ. Idiopathic pulmonary fibrosis: new insights into pathogenesis. Clinics In Chest Medicine 2004, 25: 749-758. PMID: 15564020, DOI: 10.1016/j.ccm.2004.04.003.Peer-Reviewed Original ResearchConceptsUsual interstitial pneumoniaInterstitial pneumoniaUncontrolled lung inflammationUnique pathologic featuresProgressive clinical courseAnti-inflammatory therapyIdiopathic pulmonary fibrosisLung inflammationClinical coursePathologic featuresPulmonary fibrosisCardinal manifestationsInflammatory responseNew therapiesFibroblast functionPneumoniaPathogenesisTherapyCurrent thoughtsRecent reviewBiopsyInflammationFibrosisIPF
2003
Nonspecific Interstitial Pneumonia
Homer R. Nonspecific Interstitial Pneumonia. Advances In Anatomic Pathology 2003, 8: 257-266. DOI: 10.1097/01.pcr.0000101943.54233.3e.Peer-Reviewed Original ResearchInterstitial lung diseaseNonspecific interstitial pneumoniaLung diseaseInterstitial pneumoniaDiffuse parenchymal lung diseaseConsensus classification systemIndividual patient prognosticationIdiopathic interstitial pneumoniaParenchymal lung diseaseTailoring of therapyPathologic featuresClinical featuresPatient prognosticationIndividual patientsPneumoniaDiseaseEuropean SocietyDistinct subgroupsSubgroupsWide spectrumClassification systemYearsPatientsTherapyClinicians
1999
T Helper 1 Cells and Interferon γ Regulate Allergic Airway Inflammation and Mucus Production
Cohn L, Homer R, Niu N, Bottomly K. T Helper 1 Cells and Interferon γ Regulate Allergic Airway Inflammation and Mucus Production. Journal Of Experimental Medicine 1999, 190: 1309-1318. PMID: 10544202, PMCID: PMC2195688, DOI: 10.1084/jem.190.9.1309.Peer-Reviewed Original ResearchConceptsTh1 cellsTh2 cellsMucus productionAirway eosinophiliaIFN-gammaRecipient miceAirway inflammationIFN-gamma receptor signalingT helper type 1T helper 1 cellsAllergic airway inflammationTh2 cytokine secretionHelper type 1Different inhibitory pathwaysAsthmatic patientsPathologic featuresCytokine secretionInflammatory responseRespiratory tractEosinophiliaInhibitory pathwaysMouse modelInflammationType 1Marked reduction