Disparate recovery of resting and stimulated oxidative metabolism following transient ischemia.
Duckrow RB, LaManna JS, Rosenthal M. Disparate recovery of resting and stimulated oxidative metabolism following transient ischemia. Stroke 1981, 12: 677-686. PMID: 6272454, DOI: 10.1161/01.str.12.5.677.Peer-Reviewed Original ResearchConceptsMinutes of reperfusionTransient ischemiaMetabolic dysfunctionElectrocortical activityHours of reperfusionTransient cerebral ischemiaCarotid artery ligationOxidative responseLocal blood volumeOxidative metabolic functionCerebral ischemiaIschemic intervalArtery ligationRat brainBlood volumeElectrical stimulationCerebral surfaceReperfusionIschemiaOxidative metabolismMitochondrial redox stateDysfunctionEventual recoveryMetabolic functionsDisparate recoveryCerebral compensation for chronic noradrenergic denervation induced by locus ceruleus lesion: recovery of receptor binding, isoproterenol- induced adenylate cyclase activity, and oxidative metabolism
Harik SI, Duckrow RB, LaManna JC, Rosenthal M, Sharma VK, Banerjee SP. Cerebral compensation for chronic noradrenergic denervation induced by locus ceruleus lesion: recovery of receptor binding, isoproterenol- induced adenylate cyclase activity, and oxidative metabolism. Journal Of Neuroscience 1981, 1: 641-649. PMID: 7346572, PMCID: PMC6564177, DOI: 10.1523/jneurosci.01-06-00641.1981.Peer-Reviewed Original ResearchConceptsLocus ceruleus lesionNoradrenergic denervationCerebral cortexReceptor bindingNoradrenergic receptor bindingOxidative metabolismRat cerebral cortexDirect cortical stimulationVivo oxidative metabolismBlood volume shiftsCyclic AMP generationAdenylate cyclase activityCerebral compensationNoradrenaline depletionLocus ceruleusUnilateral injectionCortical stimulationCerebral noradrenalineLong-term effectsAMP generationMonophosphate generationLesionsDenervationCyclase activityWeeksOxidative metabolic activity of cerebral cortex after fluid-percussion head injury in the cat.
Duckrow R, LaManna J, Rosenthal M, Levasseur J, Patterson J. Oxidative metabolic activity of cerebral cortex after fluid-percussion head injury in the cat. Journal Of Neurosurgery 1981, 54: 607-14. PMID: 7229699, DOI: 10.3171/jns.1981.54.5.0607.Peer-Reviewed Original ResearchConceptsPosttraumatic periodCerebral cortexBlood volumeFluid percussion head injuryCortical blood volumeImmediate posttraumatic periodLocal blood volumeOxidative metabolic activityTransient hypertensionRelationship of metabolismVascular effectsCerebral circulationHead traumaVascular toneCranial windowHead injuryTrauma altersInjuryCortical surfaceCortexCatsMetabolic activityHypertensionReflection spectrophotometryPeriod