2010
Causes and Consequences of Inadequate Management of Acute Pain
Sinatra R. Causes and Consequences of Inadequate Management of Acute Pain. Pain Medicine 2010, 11: 1859-1871. PMID: 21040438, DOI: 10.1111/j.1526-4637.2010.00983.x.Peer-Reviewed Original ResearchConceptsInadequate pain managementAcute painPain managementTolerability balanceChronic painMultimodal therapyIntense acute painSingle-agent regimensAcute pain managementSevere acute painCurrent practice guidelinesMillions of patientsAgent regimensMultiple analgesicsAnalgesic therapyPain controlAvailable therapiesClinical effectivenessPreferred treatmentPractice guidelinesUndermanaged painEffective treatmentPainSide effectsPatient healthPain definitions and assessment
Sinatra R. Pain definitions and assessment. 2010, 3-6. DOI: 10.1017/cbo9780511841378.002.Peer-Reviewed Original ResearchPresence of painPost-surgical outcomesPain-related anxietyStudy of PainNumber one causePotential tissue damageIntensity of discomfortIntroduction PainPain painPain episodesAcute painChronic painPoor adherencePain definitionPatient complaintsSurgical proceduresPainOne causeTreatment planHealth professionalsTissue damageClinical settingStress hormonesClinical contextComplex physiological processA stepwise approach to pain management
Sinatra R. A stepwise approach to pain management. 2010, 66-72. DOI: 10.1017/cbo9780511841378.012.Peer-Reviewed Original ResearchPain managementAvailable pain medicationsAdjuvant medicationsNeuraxial opioidsPain medicationPain reliefAdverse eventsOpioid analgesicsPain processingMuscle relaxantsPharmacologic principlesNMDA antagonistsLocal anestheticsAnalgesicsCommon dosesClinical settingClinical useParticular drugMedicationsStepwise approachCliniciansDrugsAnalgesiaContraindicationsOpioidsOpioids and opioid receptors
Sinatra R. Opioids and opioid receptors. 2010, 73-81. DOI: 10.1017/cbo9780511841378.013.Peer-Reviewed Original ResearchPain managementAvailable pain medicationsAdjuvant medicationsNeuraxial opioidsPain medicationPain reliefAdverse eventsOpioid analgesicsPain processingMuscle relaxantsOpioid receptorsPharmacologic principlesNMDA antagonistsLocal anestheticsAnalgesicsCommon dosesClinical settingClinical useParticular drugOpioidsMedicationsCliniciansDrugsAnalgesiaContraindications
2009
Neuraxial Analgesia with Hydromorphone, Morphine, and Fentanyl: Dosing and Safety Guidelines
McQuay H, Dabu-Bondoc S, Franco S, Sinatra R. Neuraxial Analgesia with Hydromorphone, Morphine, and Fentanyl: Dosing and Safety Guidelines. 2009, 230-244. DOI: 10.1017/cbo9780511576706.018.Peer-Reviewed Original ResearchPain managementAcute pain managementPatient-controlled analgesiaRole of anesthesiologistsAnalgesic optionsPain serviceAcute painNeuraxial analgesiaPain pathwaysSevere painChronic painPain assessmentTherapeutic guidelinesOptimal carePainAnalgesiaSafety guidelinesGuidelinesFentanylPatientsHydromorphoneMorphineChronicityPathophysiologyOptionsOral and Parenteral Opioid Analgesics for Acute Pain Management
McQuay H, Sinatra R. Oral and Parenteral Opioid Analgesics for Acute Pain Management. 2009, 188-203. DOI: 10.1017/cbo9780511576706.015.Peer-Reviewed Original ResearchAcute pain managementPain managementPatient-controlled analgesiaParenteral opioid analgesicsRole of anesthesiologistsAnalgesic optionsPain serviceAcute painPain pathwaysSevere painOpioid analgesicsChronic painPain assessmentTherapeutic guidelinesOptimal carePainAnalgesiaAnalgesicsPatientsChronicityPathophysiologyOptionsAnesthesiologistsManagementOralPatient-Controlled Analgesia Devices and Analgesic Infusion Pumps
McQuay H, Sherman B, Enu I, Sinatra R. Patient-Controlled Analgesia Devices and Analgesic Infusion Pumps. 2009, 302-322. DOI: 10.1017/cbo9780511576706.021.Peer-Reviewed Original ResearchPain managementPatient-controlled analgesia deviceAcute pain managementPatient-controlled analgesiaRole of anesthesiologistsAnalgesic optionsAnalgesia devicePain serviceAcute painPain pathwaysSevere painChronic painPain assessmentTherapeutic guidelinesOptimal carePainInfusion pumpAnalgesic infusion pumpAnalgesiaPatientsChronicityPathophysiologyOptionsAnesthesiologistsCliniciansQualitative and Quantitative Assessment of Pain
McQuay H, Welchek C, Mastrangelo L, Sinatra R, Martinez R. Qualitative and Quantitative Assessment of Pain. 2009, 147-171. DOI: 10.1017/cbo9780511576706.013.Peer-Reviewed Original ResearchPain managementAcute pain managementPatient-controlled analgesiaRole of anesthesiologistsAnalgesic optionsPain serviceAcute painPain pathwaysSevere painChronic painPain assessmentTherapeutic guidelinesOptimal carePainAnalgesiaPatientsChronicityPathophysiologyOptionsAnesthesiologistsCliniciansQuantitative assessmentIncidenceNursesPharmacistsAcute Pain Management in Patients with Opioid Dependence and Substance Abuse
McQuay H, Mitra S, Sinatra R. Acute Pain Management in Patients with Opioid Dependence and Substance Abuse. 2009, 564-580. DOI: 10.1017/cbo9780511576706.036.Peer-Reviewed Original ResearchAcute pain managementPain managementPatient-controlled analgesiaRole of anesthesiologistsAnalgesic optionsPain serviceAcute painPain pathwaysSevere painChronic painOpioid dependencePain assessmentTherapeutic guidelinesOptimal carePainSubstance abusePatientsAnalgesiaChronicityPathophysiologyOptionsAnesthesiologistsManagementCliniciansIncidence
2005
The Fentanyl HCl Patient-Controlled Transdermal System (PCTS)
Sinatra R. The Fentanyl HCl Patient-Controlled Transdermal System (PCTS). Clinical Pharmacokinetics 2005, 44: 1-6. PMID: 16156110, DOI: 10.2165/00003088-200544001-00002.Peer-Reviewed Original ResearchConceptsPain controlFentanyl HCl patient-controlled transdermal systemPatient-controlled transdermal systemUpper armTransdermal systemAcute postoperative painFentanyl HCl PatientInadequate pain controlLonger hospital stayPatient's upper armSignificant healthcare resourcesDeep vein thrombosisEpidural routeFentanyl HClPCA modalitiesAnalgesic administrationHospital stayOpioid analgesiaPostoperative painPostoperative periodPulmonary embolismSevere painVein thrombosisPostoperative recoveryChronic pain
2000
Sterility of epidural solutions—Recommendations for cost-effective use
Sevarino F, Pizarro C, Sinatra R. Sterility of epidural solutions—Recommendations for cost-effective use. Regional Anesthesia & Pain Medicine 2000, 25: 368-371. PMID: 10925932, DOI: 10.1053/rapm.2000.4148.Peer-Reviewed Original Research