2020
Effects of short-term physical training on the interleukin-15 signalling pathway and glucose tolerance in aged rats
Minuzzi L, da Conceição L, Muñoz V, Vieira R, Gaspar R, da Silva A, Cintra D, Pereira de Moura L, Ropelle E, Teixeira A, Pauli J. Effects of short-term physical training on the interleukin-15 signalling pathway and glucose tolerance in aged rats. Cytokine 2020, 137: 155306. PMID: 33010727, DOI: 10.1016/j.cyto.2020.155306.Peer-Reviewed Original ResearchConceptsAerobic physical trainingInsulin sensitivityIL-15Physical trainingGlucose toleranceInterleukin-15Elderly ratsWhole-body insulin sensitivityShort-term physical trainingSkeletal muscleLast exercise sessionExercise training protocolMesenteric fat massPhysical exercise trainingPhysical exercise protocolSkeletal muscle alterationsFourteen Wistar ratsExpression of HIF1αExercise trainingExercise protocolExercise sessionsMuscle alterationsFat massWistar ratsSupraphysiological levelsLong-term effects of moderate physical exercise during early childhood on insulin sensitivity in rats during adulthood
Pereira R, Muñoz V, Anaruma C, Gaspar R, Gaspar R, Ropelle E, Cintra D, da Silva A, Pauli J, de Moura L. Long-term effects of moderate physical exercise during early childhood on insulin sensitivity in rats during adulthood. Revista Brasileira De Educação Física E Esporte 2020, 34: 227-236. DOI: 10.11606/1807-5509202000020227.Peer-Reviewed Original ResearchModerate physical exerciseInsulin sensitivityPhysical exerciseGlycogen storesLipogenic activityGlucose uptakePancreatic insulin levelsDays/weekLower body weight gainPhysical exercise protocolBody weight gainHours/dayDays of ageHOMA-IRInsulin levelsInsulin resistanceMetabolic healthExercise protocolSwimming exerciseWistar ratsLong-term effectsBody fatPancreatic insulinAdipose tissueAnaerobic threshold
2019
Exhaustive acute exercise-induced ER stress is attenuated in IL-6-knockout mice
Pinto A, da Rocha A, Kohama E, Gaspar R, Simabuco F, Frantz F, de Moura L, Pauli J, Cintra D, Ropelle E, de Freitas E, da Silva A. Exhaustive acute exercise-induced ER stress is attenuated in IL-6-knockout mice. Journal Of Endocrinology 2019, 240: 181-193. PMID: 30400033, DOI: 10.1530/joe-18-0404.Peer-Reviewed Original ResearchConceptsIL-6 knockout miceExtensor digitorium longusPhysical exercise protocolAcute exercise protocolER stress proteinsExercise protocolIL-6WT groupIL-6 KO groupSerum levelsKO groupExercise-induced IL-6IL-6 concentrationsWild-type miceIntense physical exerciseER stressEndoplasmic reticulum stressStress proteinsIL-10Interleukin-6Knockout micePhysical exerciseSoleusHomeostatic functionsMice