Featured Publications
Enhanced Recovery After Surgery: Opioid Sparing Strategies After Discharge: A Review
Rajput K, Shergill S, Chow RM, Vadivelu N, Kaye AD. Enhanced Recovery After Surgery: Opioid Sparing Strategies After Discharge: A Review. Current Pain And Headache Reports 2022, 26: 93-102. PMID: 35072920, DOI: 10.1007/s11916-022-01009-x.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsAftercareAnalgesics, OpioidEnhanced Recovery After SurgeryHumansPain, PostoperativePatient DischargeConceptsOpioid usePersistent post-surgical painNon-opioid strategiesNon-opioid therapiesOpioid-sparing strategiesOverprescribing of opioidsPostoperative pain scoresMultimodal analgesic approachPost-surgical painSide effect profileNon-opioid analgesicsRecent FindingsSeveral studiesERAS protocolOpioid protocolAnalgesic approachBreakthrough painHospital stayMultimodal analgesiaPain scoresAcute painOral ketaminePostoperative periodEffect profilePatient recoveryGood quality researchAmbulatory Pain Management in the Pediatric Patient Population
Oliver JA, Oliver LA, Aggarwal N, Baldev K, Wood M, Makusha L, Vadivelu N, Lichtor L. Ambulatory Pain Management in the Pediatric Patient Population. Current Pain And Headache Reports 2022, 26: 15-23. PMID: 35129824, DOI: 10.1007/s11916-022-00999-y.Peer-Reviewed Original ResearchMeSH KeywordsAmbulatory Surgical ProceduresAnalgesiaAnalgesics, OpioidAnesthesia, ConductionChildHumansPain ManagementPain, PostoperativeConceptsPain managementPostoperative painPediatric ambulatory surgical patientsPostoperative pain controlAmbulatory surgical patientsSevere postoperative painExtent of painPeripheral nerve blocksPediatric ambulatory surgeryPediatric patient populationNon-pharmacological techniquesRandomized control studyEvidence-based approachMultimodal analgesiaPain controlSurgical patientsNerve blockPediatric populationAmbulatory surgeryPatient populationMost centersControl studyPainScientific evidenceMultimodal approachAcute Pain Management of Chronic Pain Patients in Ambulatory Surgery Centers
Rajput K, Vadivelu N. Acute Pain Management of Chronic Pain Patients in Ambulatory Surgery Centers. Current Pain And Headache Reports 2021, 25: 1. PMID: 33443656, DOI: 10.1007/s11916-020-00922-3.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsPerioperative pain managementAmbulatory surgery centersNon-opioid analgesicsPain managementSurgery centersIntrathecal pain pumpOpioid-tolerant patientsPostoperative opioid requirementsAcute pain managementChronic opioid useProportion of patientsSubset of patientsChronic pain patientsSame-day admission patientsSpinal cord stimulatorPurpose of ReviewWithOpioid requirementsPostoperative opioidsMalignant painMultimodal analgesiaPerioperative painOpioid toleranceOpioid usePain specialistsPain patients
2013
Comparison of immediate postoperative pain after transvaginal versus traditional laparoscopic cholecystectomy
Wood SG, Dabu-Bondoc S, Dai F, Mikhael H, Vadivelu N, Roberts KE. Comparison of immediate postoperative pain after transvaginal versus traditional laparoscopic cholecystectomy. Surgical Endoscopy 2013, 28: 1141-1145. PMID: 24232050, DOI: 10.1007/s00464-013-3294-8.Peer-Reviewed Original ResearchConceptsPost-anesthesia care unitPostoperative opioid useLaparoscopic cholecystectomyLC patientsLC groupTVC patientsOpioid requirementsPain scoresPain medicationPostoperative painOpioid useFour-port laparoscopic cholecystectomyImmediate postoperative pain managementOperating roomImmediate postoperative painIntraoperative opioid requirementsPACU pain scoresTraditional laparoscopic cholecystectomyAverage pain scorePostoperative pain managementLess pain medicationAnesthesia care unitBody mass indexTerms of agePaucity of dataClinical applications of oxymorphone.
Vadivelu N, Maria M, Jolly S, Rosenbloom J, Prasad A, Kaye AD. Clinical applications of oxymorphone. Journal Of Opioid Management 2013, 9: 439-52. PMID: 24481932, DOI: 10.5055/jom.2013.0186.Peer-Reviewed Original ResearchConceptsNew oral preparationNew oral formulationSemisynthetic opioid analgesicSpecific side effectsSevere painOpioid analgesicsParenteral formClinical indicationsOral preparationsStudy populationPharmacological considerationsOral formulationSide effectsPatient needsUS FoodDrug AdministrationHealthcare providersParenteral formulationsClinical applicationPainImportant drugsOxymorphoneAdditional optionPyridomorphinansSpecific considerationsCommon misconceptions about opioid use for pain management at the end of life.
Berger JM, Vadivelu N. Common misconceptions about opioid use for pain management at the end of life. The AMA Journal Of Ethic 2013, 15: 403-9. PMID: 23680560, DOI: 10.1001/virtualmentor.2013.15.5.ecas1-1305.Peer-Reviewed Original Research
2010
Buprenorphine in Postoperative Pain Management
Vadivelu N, Anwar M. Buprenorphine in Postoperative Pain Management. Anesthesiology Clinics 2010, 28: 601-609. PMID: 21074740, DOI: 10.1016/j.anclin.2010.08.015.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAnalgesics, OpioidBuprenorphineChronic DiseaseHumansPain, PostoperativeReceptors, Opioid
2009
Hemispheric Synchronized Sounds and Perioperative Analgesic Requirements
Dabu-Bondoc S, Vadivelu N, Benson J, Perret D, Kain ZN. Hemispheric Synchronized Sounds and Perioperative Analgesic Requirements. Anesthesia & Analgesia 2009, 110: 208-210. PMID: 19861358, DOI: 10.1213/ane.0b013e3181bea424.Peer-Reviewed Original ResearchConceptsPerioperative analgesic requirementsAnalgesic requirementsGeneral anesthesiaTreatment groupsVisual analog scale scoreIntraoperative analgesic requirementsIntraoperative fentanyl consumptionPostoperative pain scoresAnalog scale scoreFentanyl consumptionPain scoresSurgical outpatientsScale scoreControl groupAnesthesiaMusic groupScoresGroupSubjectsVecuroniumOutpatients
2008
Management of chronic pain in the elderly: focus on transdermal buprenorphine
Vadivelu N, Hines RL. Management of chronic pain in the elderly: focus on transdermal buprenorphine. Clinical Interventions In Aging 2008, Volume 3: 421-430. PMID: 18982913, PMCID: PMC2682375, DOI: 10.2147/cia.s1880.Peer-Reviewed Original ResearchConceptsChronic painTransdermal buprenorphineSafety profileChronic cancer painChronic nonmalignant painNew treatment optionsRelative safety profileCancer painNonmalignant painRespiratory depressionRenal failureTreatment optionsAnalgesic agentsCeiling doseAnalgesic propertiesPainSide effectsClinical practiceBuprenorphineOlder individualsCeiling effectsMetabolic changesDose dumpingSafe useRecent scientific studies
2007
Buprenorphine: a unique opioid with broad clinical applications.
Vadivelu N, Hines RL. Buprenorphine: a unique opioid with broad clinical applications. Journal Of Opioid Management 2007, 3: 49-58. PMID: 17367094, DOI: 10.5055/jom.2007.0038.Peer-Reviewed Original ResearchConceptsAnti-inflammatory agentsPartial mu agonistRoute of administrationUnique opioidPerioperative painAdequate analgesiaAnalgesic potentialMu agonistsBroad clinical applicationOpioid addictionAddictive potentialClinical applicationBuprenorphineAgonistsPositive resultsAnalgesiaMedicationsOpioidsPainAdministration