Featured Publications
Endometriosis Pain Management: a Review
Carlyle D, Khader T, Lam D, Vadivelu N, Shiwlochan D, Yonghee C. Endometriosis Pain Management: a Review. Current Pain And Headache Reports 2020, 24: 49. PMID: 32671581, DOI: 10.1007/s11916-020-00884-6.Peer-Reviewed Original ResearchConceptsSurgical managementGnRH agonists/antagonistsNonsteroidal anti-inflammatory drugsPain management optionsAnti-inflammatory drugsAgonists/antagonistsNerve ablationPresacral neurectomyMedical managementTreatment modalitiesAromatase inhibitorsChallenging diseaseSurgical techniqueReviewThe purposeNeurectomyExperimental pharmaceuticalsManagement optionsAblationHysterectomyOophorectomyEndometriosisRegimensResectionDanazolPatients
2016
Efficacy and Safety of Nonopioid Analgesics in Perioperative Pain Control.
Thomas DA, West M, Legler A, Maslin B, Kim RK, Vadivelu N. Efficacy and Safety of Nonopioid Analgesics in Perioperative Pain Control. Current Drug Safety 2016, 11: 196-205. PMID: 27113953, DOI: 10.2174/1574886311666160426130444.Peer-Reviewed Original ResearchConceptsPain controlNonopioid analgesicsSide effectsContemporary pain managementOptimum pain controlPerioperative pain controlAcute postoperative painPostoperative pain controlMultiple side effectsNonopioid medicationsPostoperative painTolerant patientsPain managementSafety profileAnalgesicsRecent dataComorbiditiesMedicationsOpioidsPainPatientsSurgeryMainstayControl
2014
Intrathecal drug delivery for chronic pain management-scope, limitations and future
Czernicki M, Sinovich G, Mihaylov I, Nejad B, Kunnumpurath S, Kodumudi G, Vadivelu N. Intrathecal drug delivery for chronic pain management-scope, limitations and future. Journal Of Clinical Monitoring And Computing 2014, 29: 241-249. PMID: 25173564, DOI: 10.1007/s10877-014-9607-1.Peer-Reviewed Original ResearchConceptsIntrathecal drug delivery systemsChronic painOptimal medical managementIntrathecal drug deliveryDifferent implantation techniquesLicensing of drugsSevere morbidityMedical managementMuscle spasmMain indicationsIntrathecal useInvasive techniquesOutcome studiesPainAdverse effectsHealthcare practitionersImplantation techniqueTherapyDrug delivery systemsTherapy systemReview articleDelivery systemDate knowledgeMorbiditySpasm
2013
Comparison of immediate postoperative pain after transvaginal versus traditional laparoscopic cholecystectomy
Wood SG, Dabu-Bondoc S, Dai F, Mikhael H, Vadivelu N, Roberts KE. Comparison of immediate postoperative pain after transvaginal versus traditional laparoscopic cholecystectomy. Surgical Endoscopy 2013, 28: 1141-1145. PMID: 24232050, DOI: 10.1007/s00464-013-3294-8.Peer-Reviewed Original ResearchConceptsPost-anesthesia care unitPostoperative opioid useLaparoscopic cholecystectomyLC patientsLC groupTVC patientsOpioid requirementsPain scoresPain medicationPostoperative painOpioid useFour-port laparoscopic cholecystectomyImmediate postoperative pain managementOperating roomImmediate postoperative painIntraoperative opioid requirementsPACU pain scoresTraditional laparoscopic cholecystectomyAverage pain scorePostoperative pain managementLess pain medicationAnesthesia care unitBody mass indexTerms of agePaucity of dataClinical applications of oxymorphone.
Vadivelu N, Maria M, Jolly S, Rosenbloom J, Prasad A, Kaye AD. Clinical applications of oxymorphone. Journal Of Opioid Management 2013, 9: 439-52. PMID: 24481932, DOI: 10.5055/jom.2013.0186.Peer-Reviewed Original ResearchConceptsNew oral preparationNew oral formulationSemisynthetic opioid analgesicSpecific side effectsSevere painOpioid analgesicsParenteral formClinical indicationsOral preparationsStudy populationPharmacological considerationsOral formulationSide effectsPatient needsUS FoodDrug AdministrationHealthcare providersParenteral formulationsClinical applicationPainImportant drugsOxymorphoneAdditional optionPyridomorphinansSpecific considerations
2012
Intravenous Dextrose Administration Reduces Postoperative Antiemetic Rescue Treatment Requirements and Postanesthesia Care Unit Length of Stay
Dabu-Bondoc S, Vadivelu N, Shimono C, English A, Kosarussavadi B, Dai F, Shelley K, Feinleib J. Intravenous Dextrose Administration Reduces Postoperative Antiemetic Rescue Treatment Requirements and Postanesthesia Care Unit Length of Stay. Anesthesia & Analgesia 2012, 117: 591-596. PMID: 22253268, DOI: 10.1213/ane.0b013e3182458f9e.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAmbulatory Surgical ProceduresAnesthesia, GeneralAntiemeticsCritical CareDouble-Blind MethodFemaleGlucoseGynecologic Surgical ProceduresHumansHysteroscopyInjections, IntravenousIntensive Care UnitsLaparoscopyLength of StayMiddle AgedPostoperative Nausea and VomitingSolutionsTreatment OutcomeYoung AdultConceptsPostanesthesia care unitRinger's lactate solutionDextrose administrationControl groupLactate solutionPostanesthesia care unit lengthDextrose 5Antiemetic rescue medicationIntravenous dextrose administrationPostoperative nausea scoresRate of PONVRescue antiemetic medicationRescue medication requirementsStandardized general anesthesiaPlacebo-controlled trialPostoperative hospital stayASA class ICommon postoperative complicationPONV managementPONV ratePONV scoresRescue medicationUnanticipated admissionAntiemetic medicationHospital stay
2008
Management of chronic pain in the elderly: focus on transdermal buprenorphine
Vadivelu N, Hines RL. Management of chronic pain in the elderly: focus on transdermal buprenorphine. Clinical Interventions In Aging 2008, Volume 3: 421-430. PMID: 18982913, PMCID: PMC2682375, DOI: 10.2147/cia.s1880.Peer-Reviewed Original ResearchConceptsChronic painTransdermal buprenorphineSafety profileChronic cancer painChronic nonmalignant painNew treatment optionsRelative safety profileCancer painNonmalignant painRespiratory depressionRenal failureTreatment optionsAnalgesic agentsCeiling doseAnalgesic propertiesPainSide effectsClinical practiceBuprenorphineOlder individualsCeiling effectsMetabolic changesDose dumpingSafe useRecent scientific studies
2007
Can the Shikani Optical Stylet facilitate intubation in simulated difficult direct laryngoscopy?
Young CF, Vadivelu N. Can the Shikani Optical Stylet facilitate intubation in simulated difficult direct laryngoscopy? Connecticut Medicine 2007, 71: 407-8. PMID: 17879863.Peer-Reviewed Original Research
2000
Ketamine-fentanyl-midazolam infusion for the control of symptoms in terminal life care
Berger J, Ryan A, Vadivelu N, Merriam P, Rever L, Harrison P. Ketamine-fentanyl-midazolam infusion for the control of symptoms in terminal life care. American Journal Of Hospice And Palliative Medicine® 2000, 17: 127-134. PMID: 11406957, DOI: 10.1177/104990910001700213.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAnalgesicsCognition DisordersDrug Therapy, CombinationFemaleFentanylHumansHypnotics and SedativesInfusions, IntravenousKetamineMaleMidazolamMiddle AgedNeoplasmsPainPain MeasurementPsychomotor AgitationReceptors, N-Methyl-D-AspartateRetrospective StudiesTerminal CareTreatment Outcome