2020
Mast cell activation in the systemic sclerosis esophagus
Tom K, Mehta BK, Hoffmann A, Aren K, Carns M, Lee J, Martyanov V, Popovich D, Kosarek N, Wood T, Brenner D, Carlson DA, Ostilla L, Willcocks E, Bryce P, Wechsler JB, Whitfield ML, Hinchcliff M. Mast cell activation in the systemic sclerosis esophagus. Journal Of Scleroderma And Related Disorders 2020, 6: 77-86. PMID: 34179507, PMCID: PMC8225255, DOI: 10.1177/2397198320941322.Peer-Reviewed Original ResearchMast cell numbersSSc patientsCell-directed therapiesSystemic sclerosisEsophageal biopsiesClinical parametersHealthy participantsCell numberNormal-like subsetsMast cell densityCell-targeted therapiesMast cell markersUseful therapeutic approachMast cell activationMast cell quantityRelevant clinical parametersMolecular classification systemEoE patientsEsophageal symptomsEosinophilic esophagitisUpper esophagusSkin biopsiesEntire esophagusMast cellsTherapeutic approaches
2018
Normal Values of Esophageal Distensibility and Distension-Induced Contractility Measured by Functional Luminal Imaging Probe Panometry
Carlson DA, Kou W, Lin Z, Hinchcliff M, Thakrar A, Falmagne S, Prescott J, Dorian E, Kahrilas PJ, Pandolfino JE. Normal Values of Esophageal Distensibility and Distension-Induced Contractility Measured by Functional Luminal Imaging Probe Panometry. Clinical Gastroenterology And Hepatology 2018, 17: 674-681.e1. PMID: 30081222, PMCID: PMC6360138, DOI: 10.1016/j.cgh.2018.07.042.Peer-Reviewed Original ResearchConceptsRepetitive antegrade contractionsEGJ-DIFLIP panometryDistensibility plateauAntegrade contractionsEsophageal contractilityEsophagogastric junctionEsophageal distensibilityAsymptomatic volunteersClinical practiceFunctional luminal imaging probe (FLIP) panometryEGJ-distensibility indexSedated upper endoscopyTime of endoscopyProximal esophageal bodyRAC patternUpper endoscopyDistal esophagusEosinophilic esophagitisEsophageal bodyNormal findingsProspective studyEsophageal diseaseDistal bodyHealthy individuals