2020
Automated feature quantification of Lipiodol as imaging biomarker to predict therapeutic efficacy of conventional transarterial chemoembolization of liver cancer
Stark S, Wang C, Savic LJ, Letzen B, Schobert I, Miszczuk M, Murali N, Oestmann P, Gebauer B, Lin M, Duncan J, Schlachter T, Chapiro J. Automated feature quantification of Lipiodol as imaging biomarker to predict therapeutic efficacy of conventional transarterial chemoembolization of liver cancer. Scientific Reports 2020, 10: 18026. PMID: 33093524, PMCID: PMC7582153, DOI: 10.1038/s41598-020-75120-7.Peer-Reviewed Original ResearchConceptsConventional transarterial chemoembolizationLipiodol depositionTransarterial chemoembolizationLiver cancerPeripheral depositionLipiodol depositsTherapeutic efficacyNecrotic tumor areasBaseline MRITherapy optionsTumor responseTreatment responseTumor volumeLiver lesionsLipiodolH postTumor areaH-CTHounsfield unitsBiomarkersChemoembolizationHigh rateTumorsCancerImproved response
2013
Can C-Arm Cone-Beam CT Detect a Micro-Embolic Effect After TheraSphere Radioembolization of Neuroendocrine and Carcinoid Liver Metastasis?
Pellerin O, Lin M, Bhagat N, Shao W, Geschwind J. Can C-Arm Cone-Beam CT Detect a Micro-Embolic Effect After TheraSphere Radioembolization of Neuroendocrine and Carcinoid Liver Metastasis? Cancer Biotherapy & Radiopharmaceuticals 2013, 28: 459-465. PMID: 23484809, PMCID: PMC3715773, DOI: 10.1089/cbr.2012.1390.Peer-Reviewed Original ResearchConceptsTumor enhancementHounsfield unitsArterial phaseCapillary levelCarcinoid liver metastasesYttrium-90 microspheresHigh-dose radiationEarly arterial phaseContrast medium injectionC-arm cone-beam CTTheraSphere radioembolizationLiver metastasesNeuroendocrine tumorsHepatic tumorsDelayed phasesRadioembolizationTumor densityMedium injectionTumor attenuationTumor vesselsTumorsTheraSphereEmbolic effectCone-beam CTSignificant decrease